Sort   by:  
 Page size 
TranscriptomicsDifferentiated Truncation and Uridylation Patterns of miRNAs in Arabidopsis and Rice hen1 Mutants Suggest miRNAs May Re-program RISC
miRNA levels depend on both biogenesis and turnover. The methyltransferase HEN1 stabilizes plant miRNAs, animal piRNAs, and siRNAs in both kingdoms via 3' terminal methylation. Loss of HEN1 in plants results in non-templated oligo-uridylation and accelerated degradation of miRNAs. In hen1 mutants fr...
ORGANISM(S): Arabidopsis thaliana 
2013-07-22 | E-GEOD-35562 | biostudies-arrayexpress
ProteomicsN-Acetyl-β-D-hexosaminidases mediate the generation of paucimannosidic proteins via a putative non-canonical truncation pathway in human neutrophils
We recently discovered that human neutrophils express immunomodulatory glycoproteins carrying unusual and highly truncated paucimannosidic N-glycans (Man1-3GlcNAc2Fuc0-1), but their biosynthesis remains elusive. Guided by the well-characterised truncation pathway in invertebrates and plants in which...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD027664 | Pride
N-acetyl-β-d-hexosaminidase Biosynthesis Paucimannose Truncation Neutrophil Mass spectrometry N-glycosylation 
GenomicsTruncation of the p300/CBP TAZ2 domain promotes tumor progression
Truncation of the p300/CBP TAZ2 domain promotes tumor progression
PRJNA1423281 | ENA
TranscriptomicsTruncation of LOC100288798 (SLC38A4-AS) lncRNA in human haploid KBM7 cell line
Many thousand long non-coding (lnc) RNAs are mapped in the human genome. Time consuming studies using reverse genetic approaches by post-transcriptional knock-down or genetic modification of the locus demonstrated diverse biological functions for a few of these transcripts. The Human Gene Trap Mutan...
ORGANISM(S): Homo sapiens 
2015-12-22 | E-GEOD-71284 | biostudies-arrayexpress
GenomicsFGFR2 C-terminal truncation in cancer
FGFR2 C-terminal truncation in cancer
PRJEB42514 | ENA
GenomicsCas9-guided haplotyping of three truncation variants in autosomal recessive disease
Cas9-guided haplotyping of three truncation variants in autosomal recessive disease
PRJNA806796 | ENA
GenomicsRNA-seq analysis of the budding yeast prp45(1-169) strain (a "scarless" truncation)
RNA-seq analysis of the budding yeast prp45(1-169) strain (a "scarless" truncation)
PRJEB18554 | ENA
TranscriptomicsTruncation of the p300/CBP TAZ2 domain promotes tumor progression
The histone acetyltransferase activity of p300/CBP is negatively regulated by the TAZ2 domain. Truncating mutations in the TAZ2 domain have been identified in several cancer types. Here, we show that truncation of p300/CBP at the TAZ2 domain inhibits tumor cell growth in vitro, while accelerating tu...
ORGANISM(S): Homo sapiens 
2026-08-09 | GSE319434 | GEO
UnknownCox regression model under dependent truncation.
Not available
S-EPMC8426413 | biostudies-literature
GenomicsCRISPR Activation Reverses Haploinsufficiency and Functional Deficits Caused by TTN Truncation Variants
CRISPR Activation Reverses Haploinsufficiency and Functional Deficits Caused by TTN Truncation Variants
PRJNA1076575 | ENA
Sort   by:  
 Page size