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TranscriptomicsComparison of the Global Gene Expression of Choroid Plexus and Meninges and Associated Vasculature under Control Conditions and after Pronounced Hyperthermia or Amphetamine Toxicity
These tissue were harvested to complement and extend the studies that generated GSE23093. They served 3 purposes; 1) identify genes important to choroid plexus function and compare them with those important for meninges and associated vasculature (MAV) function, 2) determine genes in the choroid pl...
ORGANISM(S): Rattus norvegicus 
2012-08-01 | E-GEOD-29733 | biostudies-arrayexpress
UnknownTrunk motion visual feedback during walking improves dynamic balance in older adults: Assessor blinded randomized controlled trial.
Not available
S-EPMC5960622 | biostudies-literature
TranscriptomicsGenome-wide cardiac gene expression analysis of mice with cardiomyocyte-specific deletion of Dnmt3a and Dnmt3b
Cardiomyocyte-specific double knockout (DKO) mice lacking the catalytic domains of Dnmt3a (exon 18) and Dnmt3b (exon 19) were obtained by mating Dnmt3aflox and Dnmt3bflox mice [PMID 15757890] with mice expressing a cre recombinase under control of the cardiac atrial myosin light chain promoter (Myl7...
ORGANISM(S): Mus musculus 
2015-06-30 | E-GEOD-68518 | biostudies-arrayexpress
TranscriptomicsAorta- and liver-specific ERalpha binding patterns and gene regulation by estrogen
Estrogen has vascular protective effects in premenopausal women and in women under 60 receiving hormone replacement therapy. However, estrogen also increases risks of breast and uterine cancers and of venous thromboses linked to upregulation of coagulation factors in the liver. In mouse models, the ...
ORGANISM(S): Mus musculus 
2014-06-30 | E-GEOD-57804 | biostudies-arrayexpress
TranscriptomicsInduction of muscle-related gene expression in loose connective tissue fibroblasts in response to static tissue stretch
Current knowledge of mechanically-induced regulation of gene expression in fibroblast is mostly based on experiments using prolonged cyclical stretching of either cultured cells or load-bearing connective tissues such as tendons and ligaments. In this study, we have examined the effect of static ti...
ORGANISM(S): Mus musculus 
2011-05-08 | E-GEOD-11371 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human neural crest cells
The expression profiles of five human trunk level neural crest cell lines were determined on Affymetrix chips HG U133 Plus 2.0. Experiment Overall Design: Total RNA was extracted from a confluent 10 cm dish of hNCC (lines N1-N5) from five human embryos at 26-32 dpf (Carnegie stages 12 & 13).
ORGANISM(S): Homo sapiens 
2009-09-13 | E-GEOD-14340 | biostudies-arrayexpress
UnknownDual-Level Pattern Tree for Visual Field Improves Glaucoma Progression and Polygenic Risk Prediction.
Not available
S-EPMC12697711 | biostudies-literature
TranscriptomicsExpression data from human sarcoma patient samples treated with either vehicle control or Nutlin-3a
This study has examined the molecular mechanisms underlying sensitivity of sarcomas to Nutlin-3a, a non-genotoxic activator of the p53 pathway. Human patient material was collected immediately following surgical resection, dissected into small pieces and ex planted onto gelatin sponges immersed in m...
ORGANISM(S): Homo sapiens 
2014-03-10 | E-GEOD-48296 | biostudies-arrayexpress
GenomicsAorta- and liver-specific ERalpha binding patterns and gene regulation by estrogen (ChIP-seq)
Estrogen has vascular protective effects in premenopausal women and in women under 60 receiving hormone replacement therapy. However, estrogen also increases risks of breast and uterine cancers and of venous thromboses linked to upregulation of coagulation factors in the liver. In mouse models, the ...
ORGANISM(S): Mus musculus 
2014-06-30 | E-GEOD-52351 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse aorta after chronic rosiglitazone treatment
To better understand what genes are regulated by PPAR gamma, an experimental dataset was generated by microarray analysis, in duplicate, of pooled aortic mRNA isolated from adult male mice (C57BL/6J strain) treated for 21 days with a PPAR gamma agonist (rosiglitazone) or vehicle.
ORGANISM(S): Mus musculus 
2008-06-11 | E-GEOD-1011 | biostudies-arrayexpress
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