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The 43S pre-initiation complex (PIC) assembly requires establishment of numerous interactions among eukaryotic initiation factors (eIFs), Met-tRNAiMet and the small ribosomal subunit (40S). Owing to several differences in the structure and composition of kinetoplastidian 40S compared to their mammal...
ORGANISM(S): Leishmania tarentolae Trypanosoma cruzi strain CL Brener 
2020-03-25 | PXD016063 | Pride
Enhancing Trypanosomatids Identification and Genotyping with Oxford Nanopore Sequencing: Development and Validation of an 18S rRNAs Amplicon-Based Method.
Barcoding project of insect and plant trypanosomatids availables at Fiocruz Protozoa Culture Collection http://colprot.fiocruz.br/ Phenotype or genotype
Genomics
DNA replication in trypanosomatids.
Genomics
Epigenetics in trypanosomatids
Development of an amplicon-based Next Generation Sequencing protocol to identify Leishmania species and other trypanosomatids in Leishmaniasis endemic areas
We developed a novel method for RNA-seq in Trypanosomatids called ‘Spliced-Leader Sequencing’ (SL-seq). The method is based on the fact that the 5’ end of Trypanosomatid mRNA is starts with a SL-sequence, and specifically enriches SL-containing RNA prior to sequencing. In this study we compared the ...
ORGANISM(S): Homo sapiens Leishmania donovani 
2017-05-30 | GSE95353 | GEO
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