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TranscriptomicsThe Repertoire and Dynamics of Evolutionary Adaptations to Controlled Nutrient-Limited Environments in Yeast
The experimental evolution of laboratory populations of microbes provides an opportunity to observe the evolutionary dynamics of adaptation in real time.Until very recently, however, such studies have been limited by our inability to systematically find mutations in evolved organisms.We overcome thi...
ORGANISM(S): Saccharomyces cerevisiae 
2010-05-18 | E-GEOD-13435 | biostudies-arrayexpress
ProteomicsThe Impacts of Surgery and Intracerebral Electrodes in C57BL/6J Mouse Kainate Model of Epileptogenesis: Seizure Threshold, Proteomics, and Cytokine Profiles
ntracranial electroencephalography (EEG) is commonly used to study epileptogenesis and epilepsy in experimental models. Chronic gliosis and neurodegeneration at the injury site are known to be associated with surgically implanted electrodes in both humans and experimental models. Currently, however,...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD021554 | Pride
Neuroinflammation Epilepsy Seizure threshold. Proinflammatory cytokines Intracerebral electrodes Traumatic brain injury Blood-brain barrier 
Proteomics24h Lingulodinium Circadian Proteome
Protein levels measured over a 24 hour period in a light dark cycle
ORGANISM(S): Lingulodinium polyedrum 
2019-12-13 | PXD006994 | Pride
Circadian Dinoflagellate 
UnknownIdentification of a rare coding variant in TREM2 in a Chinese individual with Alzheimer's disease.
Not available
S-EPMC5639900 | biostudies-literature
TranscriptomicsBrown Adipose Tissue Harbors a distinct subpopulation of regulatory T cells
Regulatory T (Treg) cells are critical determinants of both immune responses and metabolic control. Here we show that systemic ablation of Treg cells compromised the adaptation of whole-body energy expenditure to cold exposure, correlating with impairment in thermogenic marker gene expression and ma...
ORGANISM(S): Mus musculus 
2015-06-23 | E-GEOD-64909 | biostudies-arrayexpress
UnknownGlioblastoma Neurovascular Progenitor Orchestrates Tumor Cell Type Diversity.
Not available
S-EPMC11291138 | biostudies-literature
GenomicsInvestigating the requirement of H3K14 and H3P16 for optimal H3K4me3
ChIP-seq experiment for histone H3 and H3K4me3 from wild-type Saccharomyces cerevisiae (WT) and strains in which H3K14 has been substituted for alanine (K14A) or H3P16 has been substituted with valine (P16V).
ORGANISM(S): Saccharomyces cerevisiae 
2014-07-22 | E-MTAB-2717 | biostudies-arrayexpress
UnknownLarge dataset enables prediction of repair after CRISPR-Cas9 editing in primary T cells.
Not available
S-EPMC7388783 | biostudies-literature
UnknownCryo-EM reconstruction of heavy chain mouse apoferritin, 8 datasets testing dose rate and correlative double sampling mode for the Gatan K3 direct electron detector. [1143 multi-frame micrographs composed of 120 frames in LZW compressed TIFF format
Not available
EMPIAR-10588 | biostudies-other
UnknownClinical efficacy of gene-modified stem cells in adenosine deaminase-deficient immunodeficiency.
Not available
S-EPMC5409097 | biostudies-literature
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