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UnknownDual angiotensin receptor and neprilysin inhibition as an alternative to angiotensin-converting enzyme inhibition in patients with chronic systolic heart failure: rationale for and design of the Prospective comparison of ARNI with ACEI to Determine Impact on Global Mortality and morbidity in Heart Failure trial (PARADIGM-HF).
Not available
S-EPMC3746839 | biostudies-literature
UnknownPSCs Reveal PUFA-Provoked Mitochondrial Stress as a Central Node Potentiating RPE Degeneration in Bietti's Crystalline Dystrophy.
Not available
S-EPMC7704739 | biostudies-literature
GenomicsTranscriptional Pause Release Is a Rate-Limiting Step for Somatic Cell Reprogramming (ChIP-seq)
Reactivation of the pluripotency network during somatic cell reprogramming by exogenous transcription factors involves chromatin remodeling and the recruitment of RNA polymerase II (Pol II) to target loci. Here, we report that Pol II is engaged at pluripotency promoters in reprogramming but remains ...
ORGANISM(S): Mus musculus 
2014-10-07 | E-GEOD-59828 | biostudies-arrayexpress
TranscriptomicsTranscriptional Pause Release Is a Rate-Limiting Step for Somatic Cell Reprogramming (RNA-seq)
Reactivation of the pluripotency network during somatic cell reprogramming by exogenous transcription factors involves chromatin remodeling and the recruitment of RNA polymerase II (Pol II) to target loci. Here, we report that Pol II is engaged at pluripotency promoters in reprogramming but remains ...
ORGANISM(S): Mus musculus 
2014-10-07 | E-GEOD-59813 | biostudies-arrayexpress
UnknownFumarylacetoacetate Hydrolase Knock-out Rabbit Model for Hereditary Tyrosinemia Type 1.
Not available
S-EPMC5377789 | biostudies-literature
UnknownManagement of patients with transvalvular right ventricular leads undergoing transcatheter tricuspid valve interventions: a scientific statement of the European Heart Rhythm Association and the European Association of Percutaneous Cardiovascular Interventions of the ESC endorsed by the Heart Rhythm Society, the Asian Pacific Heart Rhythm Society and the Canadian Heart Rhythm Society.
Not available
S-EPMC12077151 | biostudies-literature
ProteomicsKinase Selectivity Profiling of anti-MRSA Diarylimidazoles in HEK293 Cells
Antimicrobial resistance (AMR) is widely acknowledged as one of the most serious public health threats facing the world, yet the private sector finds it challenging to generate much-needed medicines. As an alternative discovery approach, a small array of diarylimidazoles was screened against the ESK...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD040208 | Pride
Diarylimidazole Mib-ms Kinases Hek293 Antimicrobials 
UnknownClinical analysis and pluripotent stem cells-based model reveal possible impacts of ACE2 and lung progenitor cells on infants vulnerable to COVID-19.
Not available
S-EPMC7797681 | biostudies-literature
UnknownEuropean Society of Cardiology (ESC) clinical consensus statement on indications for conduction system pacing, with special contribution of the European Heart Rhythm Association of the ESC and endorsed by the Asia Pacific Heart Rhythm Society, the Canadian Heart Rhythm Society, the Heart Rhythm Society, and the Latin American Heart Rhythm Society.
Not available
S-EPMC11957271 | biostudies-literature
UnknownA polygenic risk score improves risk stratification of coronary artery disease: a large-scale prospective Chinese cohort study.
Not available
S-EPMC9076396 | biostudies-literature
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