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ProteomicsRecombinant TSP1 cleaved by HTRA1 (LCMS)
HTRA1 proteolysis of TSP1 inhibits immune suppression in age-related macular degeneration. A minor haplotype of the 10q26 locus conveys the strongest genetic risk for age related macular degeneration (AMD), a major cause of blindness affecting millions of individuals worldwide. Here we show that mo...
ORGANISM(S): Homo sapiens (Human) 
2020-07-25 | PXD020546 | Pride
Tsp1 Htra1 
GenomicsEffect of TSP1 on gene expression of mice mPFC
Effect of TSP1 on gene expression of mice mPFC
PRJNA942936 | ENA
ModelsVenkatraman2012 - Interplay between PLS and TSP1 in TGF-β1 activation
Venkatraman2012 - Interplay between PLS and TSP1 in TGF-β1 activation The interplay between PLS (Plasmin) and TSP1 (Thrombospondin-1) in TGF-β1 (Transforming growth factor-β1)is shown using mathematical modelling and in vitro experimentents. ...
2024-09-02 | BIOMD0000000447 | BioModels
TranscriptomicsTranscription profiling of mouse colon carcinomas over-expressing c-Myc
MycRas vs Ras colon carcinoma. Human adenocarcinomas commonly harbor mutations in the Ki-Ras and c-Myc proto-oncogenes and the trp53 tumor suppressor gene. All three genetic lesions are potentially pro-angiogenic, since they sustain production of the vascular endothelial growth factor (VEGF). Yet m...
ORGANISM(S): Mus musculus 
2006-09-08 | E-MEXP-757 | biostudies-arrayexpress
ProteomicsEffect of TSP1 on peotein expression of mice mPFC
To investigate the role of TSP1 in the brain, we established the mPFC in mice after treatment with recombinant human thrombospondin-1 protein i.p.
ORGANISM(S): Mus <genus> 
2023-03-07 | PXD040646 |
UnknownThrombospondin1 (TSP1) replacement prevents cerebral cavernous malformations.
Not available
S-EPMC5679163 | biostudies-literature
TranscriptomicsEffect of TSP1 on gene expression of mice mPFC
To investigate the role of TSP1 in the brain, we established the mPFC in mice after treatment with recombinant human thrombospondin-1 protein i.p.
ORGANISM(S): Mus musculus 
2023-03-12 | GSE227035 | GEO
GenomicsGene expression profiling of Tsp1 deficient rat aortic smooth muscle cells with mechanical stretch
Gene expression profiling of Tsp1 deficient rat aortic smooth muscle cells with mechanical stretch
PRJNA544677 | ENA
UnknownPredictive model identifies strategies to enhance TSP1-mediated apoptosis signaling.
Not available
S-EPMC5735807 | biostudies-literature
UnknownPP2A Affects Angiogenesis via Its Interaction with a Novel Phosphorylation Site of TSP1.
Not available
S-EPMC10855381 | biostudies-literature
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