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ProteomicsTyrosine phosphorylation regulates RIPK1 activity to limit cell death and inflammation
Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) is a cytosolic protein kinase that regulates multiple inflammatory and cell death pathways. Serine/Threonine phosphorylation of RIPK1 is known to suppress RIPK1 kinase-mediated cell death in the contexts of inflammation, infection and em...
ORGANISM(S): Homo sapiens (Human) 
2022-10-12 | PXD036995 | Pride
Inflammation Phosphorylation Ripk1 Cell death 
TranscriptomicsGene expression patterns in human liver cancers
All the array experiments published in "Gene expression patterns in human liver cancers" by Chen X, et al. Hepatocellular carcinoma (HCC) is a leading cause of death worldwide. Using cDNA microarrays to characterize patterns of gene expression in HCC, we found consistent differences between the expr...
ORGANISM(S): Homo sapiens 
2005-10-25 | E-GEOD-3500 | biostudies-arrayexpress
ProteomicsClpP participates in stress response, biofilm formation, antimicrobials tolerance, and virulence of Enterococcus faecalis and its global substrate proteins were identified by mass spectrometer with Tandem Mass Tags (TMT) labeling
ClpP is important for bacterial growth and plays an indispensable role in cellular protein quality control systems by refolding or degrading damaged proteins, but the role of ClpP on Enterococcus faecalis is still obscure. A clpP deletion mutant (△clpP) was constructed in E. faecalis strain OG1RF in...
ORGANISM(S): Enterococcus faecalis (Streptococcus faecalis) 
2020-03-06 | PXD014211 | Pride
Enterococcus faecalis  clpp  stress tolerance  biofilm formation  virulence 
Transcriptomicsp53 and p73 ChIP-chip experiments in HCT116-3(6) cells
The p53-family of transcription factors share a highly homologous DNA binding domain and have overlapping and distinct biological functions. Using chromatin immunoprecipitation in combination with NimbleGen promoter arrays and a Model-based Algorithm for Promoter arrays (MAP), we performed a direct ...
ORGANISM(S): Homo sapiens 
2009-06-30 | E-GEOD-12224 | biostudies-arrayexpress
UnknownCytoplasm protein GFAP magnetic beads construction and application as cell separation target for brain tumors.
Not available
S-EPMC7673097 | biostudies-literature
UnknownThe association between weekend warrior physical activity pattern and anxiety: evidence from a U.S. population-based study.
Not available
S-EPMC11863453 | biostudies-literature
UnknownRho GTPase activity crosstalk mediated by Arhgef11 and Arhgef12 coordinates cell protrusion-retraction cycles.
Not available
S-EPMC10724141 | biostudies-literature
TranscriptomicsTOV112D cells treated with NSC319726
Rescuing the function of mutant p53 protein is an attractive cancer therapeutic strategy. Using the NCI anticancer drug screen data, we identified two compounds from the thiosemicarbazone family that manifest increased growth inhibitory activity in mutant p53 cells, particularly for the p53R175 muta...
ORGANISM(S): Homo sapiens 
2012-02-22 | E-GEOD-35972 | biostudies-arrayexpress
UnknownCombination strategies to optimize the efficacy of chimeric antigen receptor T cell therapy in haematological malignancies.
Not available
S-EPMC9460961 | biostudies-literature
UnknownMicroRNA-148a-3p suppresses epithelial-to-mesenchymal transition and stemness properties via Wnt1-mediated Wnt/β-catenin pathway in pancreatic cancer.
Not available
S-EPMC7701524 | biostudies-literature
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