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To further investigate the molecular mechanisms by which EVs mediated the abnormal localization of tight junction proteins and adherence junction protein, we performed miRNA microarray analysis of extracellular vesicles isolated from breast cancer cells. miRNA expression in extracellular vesicles wa...
ORGANISM(S): Homo sapiens 
Transcriptional comparison of B16F10 cells with B16F10 cell-derived extracellular vesicles (EVs) to identify transcripts enriched or de-enriched in EVs compared to their donor cells.
ORGANISM(S): Mus musculus 
To investigate the mRNA expression after extracellular vesicles or miRNA treatement, global gene expression analysis was performed in endothelial cells after the transfection of N.C. or miR-181c and or after the addition of extracellular vesicles from cancer cells. mRNA expression in brain endotheli...
ORGANISM(S): Macaca fascicularis 
Tumor-derived Small Extracellular Vesicles Inhibit CAR T Cells
Small RNAseq using tumor-derived extracellular vesicles
To investigate the impact of tumor-cell derived extracellular vesicles (EVs) on cancer-associated fibroblasts (CAFs) secretory phenotypes, CAFs were treated with pancreatic cancer cell line-derived EVs and produced extracellular matrices (ECM). ECMs denuded of cells were analyzed by mass spectrometr...
ORGANISM(S): Homo sapiens (Human) 
2026-06-11 | PXD039279 | Pride
We investigated transcriptional changes in lymph node resident lymphatic endothelial cells and medullary sinus macrophages upon interactions with melanoma cell-derived extracellular vesicles using single-cell RNA sequencing.
ORGANISM(S): Mus musculus 
Exosomes constitute an evolutionary conserved mechanism of intercellular signaling. Their importance are gaining increasing such as prognostic and diagnostic markers, and potential therapeutic tool. Merkel cell carcinoma (MCC) is an aggressive form of skin cancer with a poor prognosis. There are not...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-10-21 | MSV000080262 | MassIVE
Tumor-derived extracellular vesicles (EVs) have been associated with cancer progression and metastasis due to the transfer of bioactive molecules in between the tumor microenvironment. Although Transforming Growth Factor-β (TGF-β) signaling associated molecules have been implicated as cargo of EVs, ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD039591 | Pride
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