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TranscriptomicsDifferential in vivo tumorigenicity of distinct subpopulations from a luminal-like breast cancer model (SNP)
The cellular heterogeneity of one patient derived orthotopic breast cancer xenograft model PDX was investigated using flow cytometry, combined with assessment of in vivo tumorigenicity and SNP genotyping array for copy number analysis. Epithelial cell adhesion molecule (EpCAM) was revealed as a high...
ORGANISM(S): Homo sapiens 
2015-05-26 | E-GEOD-54595 | biostudies-arrayexpress
TranscriptomicsSystem-Wide Analysis Reveals a Complex Network of Tumor-Fibroblast Interactions Involved in Tumorigenicity
We’ve undertaken a genome-wide approach to identify and test genes in fibroblasts that are both induced upon interaction with basal breast cancer cells in culture and upregulated in stromal cells from primary human breast cancers. Several of the upregulated genes encode secreted growth factors or...
ORGANISM(S): Homo sapiens 
2013-11-21 | E-GEOD-41678 | biostudies-arrayexpress
TranscriptomicsDifferential in vivo tumorigenicity of distinct subpopulations from a luminal-like breast cancer model (expression)
The cellular heterogeneity of one patient derived orthotopic breast cancer xenograft model (PDBCX) was investigated using flow cytometry , combined with assessment of in vivo tumorigenicity and whole genome expression profiling. Epithelial cell adhesion molecule (EpCAM) was revealed as a highly spec...
ORGANISM(S): Homo sapiens 
2015-05-26 | E-GEOD-48384 | biostudies-arrayexpress
TranscriptomicsGlucose Metabolic Remodeling through Phosphoenolpyruvate Carboxykinase Isoform 2 Regulates Prostate Cancer Cell Tumorigenicity
Patients with aggressive prostate cancer generally present with poor outcomes. Identifying the factors regulating prostate cancer aggressiveness may open new avenues in therapy. Specifically, information from prostate cancer patient databases revealed that higher phosphoenolpyruvate carboxykinase is...
ORGANISM(S): Homo sapiens 
2016-01-04 | E-GEOD-76470 | biostudies-arrayexpress
GenomicsArsenic regulates ALKBH1 abundance and substrate specificity to promote translation and tumorigenicity
Arsenic regulates ALKBH1 abundance and substrate specificity to promote translation and tumorigenicity
PRJNA1206753 | ENA
ProteomicsMAP2K6 Directly Phosphorylates BCL2L13 to Mediate Mitophagy for Suppressing Tumorigenicity
Raw MS data of proteomic or phosphoproteomic in A549 cells
ORGANISM(S): Homo Sapiens 
2026-02-26 | PXD074976 |
GenomicsEpigenetic regulation of MYC modulates glioblastoma tumorigenicity
One aspect of intra-tumoral heterogeneity in glioblastoma involves subpopulations of cells capable of self-renewal and indefinite propagation. Conceptually, this capacity is frequently treated as a static property. Here we provide data suggesting that tumorigenicity in glioblastomais a dynamic prope...
ORGANISM(S): Homo sapiens 
2014-03-28 | GSE56316 | GEO
TranscriptomicsEpigenetic regulation of MYC modulates glioblastoma tumorigenicity
One aspect of intra-tumoral heterogeneity in glioblastoma involves subpopulations of cells capable of self-renewal and indefinite propagation. Conceptually, this capacity is frequently treated as a static property. Here we provide data suggesting that tumorigenicity in glioblastomais a dynamic prope...
ORGANISM(S): Homo sapiens 
2014-03-28 | E-GEOD-56316 | biostudies-arrayexpress
GenomicsTGF-b-activated LncRNA LINC00115 is a critical regulator for glioma stem-like cell tumorigenicity
TGF-b-activated LncRNA LINC00115 is a critical regulator for glioma stem-like cell tumorigenicity
PRJNA555792 | ENA
GenomicsPD-L1 alteration in lung cancer affects tumorigenicity lung tumors
PD-L1 alteration in lung cancer affects tumorigenicity lung tumors
PRJNA720411 | ENA
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