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TranscriptomicsCNV data:Clonal evolution of longitudinally sampled triple negative breast cancers using tumour and cell-free genomic sequencing
Triple Negative Breast Cancer (TNBC) is an aggressive subtype of breast cancer with high intra-tumoral heterogeneity, frequently resistant to treatment and no known targeted therapy available to improve patient outcomes. It has been hypothesized that the genomic architecture of a TNBC tumour evolves...
ORGANISM(S): Homo sapiens 
2022-12-30 | E-MTAB-11909 | biostudies-arrayexpress
TranscriptomicsPredicting the evolution of metastatic disease in breast cancer: results from 50 years of autopsies
This is a genomic analysis of breast cancer metastasis using array based CGH and is part of a large study investigating the patterns and evolution of metastases from breast cancer using autopsy material accumulated over the last 50 years from a single institution. The samples used in the genomic pro...
ORGANISM(S): Homo sapiens 
2013-11-11 | E-GEOD-46826 | biostudies-arrayexpress
GenomicsUltradeep sequening data: Clonal evolution of longitudinally sampled triple negative breast cancers using tumour and cell-free genomic sequencing
Triple Negative Breast Cancer (TNBC) is an aggressive subtype of breast cancer with high intra-tumoral heterogeneity, frequently resistant to treatment and no known targeted therapy available to improve patient outcomes. It has been hypothesized that the genomic architecture of a TNBC tumour evolves...
ORGANISM(S): Homo sapiens 
2023-08-18 | E-MTAB-11376 | biostudies-arrayexpress
GenomicsExome data: Clonal evolution of longitudinally sampled triple negative breast cancers using tumour and cell-free genomic sequencing
Triple Negative Breast Cancer (TNBC) is an aggressive subtype of breast cancer with high intra-tumoral heterogeneity, frequently resistant to treatment and no known targeted therapy available to improve patient outcomes. It has been hypothesized that the genomic architecture of a TNBC tumour evolves...
ORGANISM(S): Homo sapiens 
2023-08-09 | E-MTAB-11379 | biostudies-arrayexpress
UnknownSpatial structure governs the mode of tumour evolution.
Not available
S-EPMC8825284 | biostudies-literature
TranscriptomicsTranscriptome data-Clonal evolution of longitudinally sampled triple negative breast cancers using tumour and cell-free genomic sequencing
Triple Negative Breast Cancer (TNBC) is an aggressive subtype of breast cancer with high intra-tumoral heterogeneity, frequently resistant to treatment and no known targeted therapy available to improve patient outcomes. It has been hypothesized that the genomic architecture of a TNBC tumour evolves...
ORGANISM(S): Homo sapiens 
2023-08-09 | E-MTAB-11375 | biostudies-arrayexpress
TranscriptomicsClonal evolution and devolution following chemotherapy in adult acute myelogenous leukemia
The frequent occurrence of persistent or relapsed disease following induction chemotherapy in AML necessitates a better understanding of the clonal relationship of AML in various disease phases. In this study, we employed SNP 6.0 array-based genomic profiling of acquired copy number aberrations (aCN...
ORGANISM(S): Homo sapiens 
2013-02-12 | E-GEOD-41646 | biostudies-arrayexpress
UnknownThe ten-year evolutionary trajectory of a highly recurrent paediatric high grade neuroepithelial tumour with MN1:BEND2 fusion.
Not available
S-EPMC5773598 | biostudies-literature
UnknownSelection of metastasis competent subclones in the tumour interior.
Not available
S-EPMC7611703 | biostudies-literature
ProteomicsTumour cells can escape antiproliferative pressure by type I interferon through immunoediting of interferon receptor expression
Type I interferons (IFNs) play a central role in innate immunity against virus infection, but also in the antitumour response. In tumour biology, an important mechanism of action apart from the more indirect immune-modulatory and anti-angiogenic effects of IFNs, is their direct impact on cell prolif...
ORGANISM(S): Homo sapiens (Human) 
2023-11-21 | PXD043761 | Pride
Interferon signalling Immunoediting Cell proliferation Tumour evolution Liver cancer 
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