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MetabolomicsEffects of hypoxic preconditioning on neuroblastoma tumour oxygenation and metabolic signature in a chick embryo model
Hypoxia episodes and areas in tumours have been associated with metastatic dissemination and poor prognosis. Given the link between tumour tissue oxygen levels and cellular metabolic activity, we hypothesised that the metabolic profile between metastatic and non-metastatic tumours would reveal poten...
2018-08-13 | MTBLS541 | MetaboLights
MetabolomicsCancer-cell-secreted exosomal miR-105 promotes tumour growth through the Myc-dependent metabolic reprogramming of stromal cells
Cancer and other cells residing in the same niche engage various modes of interactions to synchronize and to buffer the negative effects of environmental changes. Extracellular miRNAs have been recently implicated in the intercellular crosstalk. Here we show a mechanistic model involving breast-canc...
2018-07-10 | MTBLS626 | MetaboLights
TranscriptomicsGene expression profiling of tumor stroma in human intrahepatic cholangiocarcinoma
Intrahepatic cholangiocarcinoma (ICC) is the second most common type of primary cancer in the liver. ICC is an aggressive cancer with poor prognosis and limited therapeutic strategies. The identification of new drug targets and prognostic biomarkers is an important clinical challenge for ICC. The pr...
ORGANISM(S): Homo sapiens 
2013-06-21 | E-GEOD-45001 | biostudies-arrayexpress
GenomicsNext Generation Sequencing Facilitates Quantitative Analysis of Transcriptomes for advanced gastric cancer with different tumour-stroma-scores
Next Generation Sequencing Facilitates Quantitative Analysis of Transcriptomes for advanced gastric cancer with different tumour-stroma-scores
PRJNA743008 | ENA
UnknownTargeting the tumour stroma to improve cancer therapy.
Not available
S-EPMC5960434 | biostudies-literature
UnknownTumour-stroma ratio and prognosis in gastric adenocarcinoma.
Not available
S-EPMC6133938 | biostudies-literature
TranscriptomicsTranscription profiling of microdissected human pancreatic tissues and pancreas cell lines (data in addition to E-MEXP-950)
Gene expression of pancreas ductal adenocarcinoma, normal duct cells, tumor stroma and stroma of chronic pancreatitis as well as of several cell lines. All primary tissue samples were microdissected. It is an addition of the data set E-MEXP-950.
ORGANISM(S): Homo sapiens 
2007-06-18 | E-MEXP-1121 | biostudies-arrayexpress
UnknownThe prognostic impact of the tumour stroma fraction: A machine learning-based analysis in 16 human solid tumour types.
Not available
S-EPMC7960932 | biostudies-literature
GenomicsIntra-tumour heterogeneity of Diffuse Large B-cell Lymphoma involves the induction of diversified stroma-tumour interfaces
Intra-tumour heterogeneity of Diffuse Large B-cell Lymphoma involves the induction of diversified stroma-tumour interfaces
PRJNA663338 | ENA
TranscriptomicsCopy Number Variation in Neuroblastoma
Neuroblastoma is a tumour of the sympathetic nervous system, with a clinical phenotype resulting from complex patterns of genetic abnormalities, accounting for the most common extracranial neoplasia in childhood. Here we report 44 copy number variations, validated by qPCR, in paired tumour and blood...
ORGANISM(S): Homo sapiens 
2014-01-01 | E-GEOD-43454 | biostudies-arrayexpress
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