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Members of the phylum Bacteroidota utilize the type IX secretion system (T9SS) to transport diverse substrates into the environment or onto their surface. T9SS substrates feature a Sec-dependent signal peptide for export to the periplasm and a conserved C-terminal domain (CTD), recognized by the T9S...
ORGANISM(S): Flavobacterium johnsoniae 
2025-09-03 | PXD065655 | Pride
The Type IX Secretion System exports proteins across the outer membrane (OM) of bacteria in the Bacteroidota phylum, however, the mechanistic details remain unknown. Here, we present a 3.5 angstrom cryo-EM structure of the periplasmic rings comprising 32-33 subunits each of PorK and PorN. Additional...
ORGANISM(S): Porphyromonas gingivalis W50 
2025-08-25 | PXD062800 | Pride
The Type IX Secretion System exports proteins across the outer membrane (OM) of bacteria in the Bacteroidota phylum, however, the mechanistic details remain unknown. Here, we present a ~3.5Å cryo-EM structure of the periplasmic rings comprising 32-33 subunits each of PorK and PorN. Additionally, we ...
ORGANISM(S): Porphyromonas gingivalis ATCC 33277 Porphyromonas gingivalis (strain ATCC BAA-308 / W83) 
2025-07-21 | PXD062825 | Pride
Prevotella intermedia is a Gram-negative bacterium that is notably linked to periodontitis and acute necrotizing ulcerative gingivitis. P. intermedia is known to utilise the T9SS to secrete and anchor virulence factors to the cell surface, presumably via C-terminal modification of the cargo protein ...
ORGANISM(S): Prevotella intermedia ATCC 25611 = DSM 20706 
2025-05-07 | PXD057272 | Pride
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