Sort   by:  
 Page size 
TranscriptomicsTranscription profiling by array of the compound U0126 in PC3 prostate cancer cells
Transcription profiling by array of the compound U0126 in PC3 prostate cancer cells
ORGANISM(S): Homo sapiens 
2014-02-09 | E-MTAB-2142 | biostudies-arrayexpress
GenomicsGene expression profiles of rat hypertrophic zone after treatment of CNP53 or U0126 [U0126]
Gene expression profiles of rat hypertrophic zone after treatment of CNP53 or U0126 [U0126]
PRJNA448590 | ENA
TranscriptomicsHuman monocyte-derived dendritic cells treated with U0126 or SB203580
Identification of MEK-ERK or p38MAPK dependent genes in human monocyte derived dendritic cells. Dendritic cells (DC) promote tolerance or immunity depending on their maturation state. Previous studies have revealed that DC maturation is enhanced or accelerated upon MEK-ERK signaling pathway inhibiti...
ORGANISM(S): Homo sapiens 
2013-05-03 | E-GEOD-39745 | biostudies-arrayexpress
TranscriptomicsSuppression of IFN-induced transcription underlies IFN defects generated by activated Ras/MEK in human cancer cells
Certain oncolytic viruses exploit activated Ras signalling in order to replicate in cancer cells. Constitutive activation of the Ras/MEK pathway is known to suppress the effectiveness of the interferon (IFN) antiviral response, which may contribute to Ras-dependent viral oncolysis. Here, we identifi...
ORGANISM(S): Homo sapiens 
2012-08-02 | E-GEOD-31019 | biostudies-arrayexpress
GenomicsExpression data from colorectal carcinoma HCT-15 treated with oncolytic virus M1 and U0126
Expression data from colorectal carcinoma HCT-15 treated with oncolytic virus M1 and U0126
PRJNA555317 | ENA
TranscriptomicsTranscription profiling of rat chondrocytes were treated with TNF-a with or without the MEK1/2 inhibitor U0126 for 24 h to investigate TNF-a-induced MEK/ERK-dependent regulation of Cartilage Matrix Genes
TNF-a is increased in the synovial fluid of patients with rheumatoid arthritis and osteoarthritis. TNF-a activates MEK/ERK in chondrocytes; however the overall functional relevance of MEK/ERK to TNF-a-regulated gene expression in chondrocytes is unknown. Chondrocytes were treated with TNF-a with or...
ORGANISM(S): Rattus norvegicus 
2009-01-17 | E-GEOD-14402 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of rat hypertrophic zone after treatment of CNP53 or U0126 [U0126]
To investigate the similarity of gene expression profile of CNP53 and U0126 treatment in growth plate.
ORGANISM(S): Rattus norvegicus 
2018-04-04 | GSE112638 | GEO
ProteomicsPhosphoproteomic analysis of Hemin- and Erastin-induced neuronal death
Analysis of the differences in phosphorylation in two ferroptosis subtypes (Hemin vs classical erastin-induced ferroptosis) in neurons, and sensitivity of these changes in phosphorylation levels to treatment with ferroptosis suppressor and MEK inhibitor U0126.
ORGANISM(S): Mus musculus (Mouse) 
2022-01-28 | PXD029318 | Pride
Erastin Hemin Tmt U0126 Ferroptosis Phosphorylation 
TranscriptomicsExpression data from colorectal carcinoma HCT-15 treated with oncolytic virus M1 and U0126
Virus infection is a kind of immune stimulation, we previously found that inhibition of Ras signaling by U0126 supress the infection of M1 virus, thus we predicted that U0126 might increase the antiviral effect, ultimately inhibit the replication of M1 virus. We plan to figure it out from the expres...
ORGANISM(S): Homo sapiens 
2019-07-19 | GSE134487 | GEO
TranscriptomicsNonwoven-based gelatin/polycaprolactone membrane loaded with ERK inhibitor U0126 for treatment of tendon defects
Background: Tendon is a major component of musculoskeletal system connecting the muscles to the bone. Tendon injuries are very common orthopedics problems leading to impeded motion. Up to now, there still lacks effective treatments for tendon diseases. Methods: Tendon stem/progenitor cells (TSPCs) w...
ORGANISM(S): Rattus norvegicus 
2022-12-10 | GSE190685 | GEO
Sort   by:  
 Page size