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Expression data from U251-shCtrl and U251-shCPVL cells
RNA sequencing facilitates quantitative analysis of U251-NC and U251-COL8A1 transcriptomes
U251 cells were treated with Vinblastine or Taxol and phosphotyrosine signaling was measured.
ORGANISM(S): Homo sapiens (Human) 
2018-11-30 | PXD008939 | Pride
Missense mutations in the TP53 gene are frequent genetic alterations in human tumor tissue and cell lines. In contrast to wild-type p53, the mutant p53 (mutp53) protein has lost the transcriptional activity towards pro-apoptotic and growth arrest genes, but retained the property to interact with DNA...
ORGANISM(S): Homo sapiens 
Cyclophosphamide (CPA) treatment on a six-day repeating metronomic schedule induces a dramatic, innate immune cell-dependent regression of implanted gliomas. However, little is known about the underlying mechanisms of innate immune cell mobilization and recruitment, or about the role of DNA damage a...
ORGANISM(S): Homo sapiens 
Cyclophosphamide (CPA) treatment on a six-day repeating metronomic schedule induces a dramatic, innate immune cell-dependent regression of implanted gliomas. However, little is known about the underlying mechanisms of innate immune cell mobilization and recruitment, or about the role of DNA damage a...
ORGANISM(S): Homo sapiens 
Missense point mutations in the TP53 gene are frequent genetic alterations in human tumor tissue and cell lines derived thereof. Mutant p53 (mutp53) proteins have lost sequence-specific DNA binding, but have retained the ability to interact in a structure-selective manner with non-B DNA and to act a...
ORGANISM(S): Homo sapiens 
miRNAseq of U251 cell line
Mechanism of Nootkatone in U251
Mechanism of Nootkatone in U251
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