U4 snrna - OmicsDI

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SHAPE-Seq of human U2 snRNA and U4 pre-snRNA

Spliceosomal snRNA are key components of small nuclear ribonucleoprotein particles (snRNPs), the building blocks of the spliceosome. The biogenesis of snRNPs is a complex process involving multiple cellular and subcellular compartments, the details of which are yet to be described. In short, the snR...

ORGANISM(S): Homo sapiens

2023-09-08 | E-MTAB-13248 | biostudies-arrayexpress

Identification of interacting proteins with U4 snRNA with and without USP39

RNA splicing and protein degradation systems allow the functional adaptation of the proteome in response to changing cellular contexts. However, the regulatory mechanisms connecting these processes remain poorly understood. Here, we show that impaired spliceosome assembly caused by USP39 deficiency ...

ORGANISM(S): Homo sapiens (Human)

2024-09-25 | PXD050688 | Pride