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ProteomicsA bioinformatics approach for integrated transcriptomic and proteomic comparative analyses of model and non-sequenced anopheline vectors of human malaria parasites
Malaria morbidity and mortality caused by both Plasmodium falciparum and Plasmodium vivax extend well beyond the African continent, and, although P. vivax causes 80-300 million severe cases each year, vivax transmission remains poorly understood. Plasmodium parasites are transmitted by Anopheles mo...
ORGANISM(S): Albimanus 
2012-11-02 | PXD000062 | Pride
Gambiae Lc ms/ms Bioinformatics Transcriptomics Albimanus Proteomics 
ProteomicsProteomic analysis of the Plasmodium male gamete reveals a key role for glycolysis in flagellar motility
Gametogenesis and fertilization play crucial roles in malaria transmission. While male gametes are thought to be amongst the simplest eukaryotic cells and are proven targets of transmission blocking immunity, little is known about their molecular organization. For example, the pathways of energy met...
ORGANISM(S): Plasmodium sp. pBT9 
2014-08-18 | PXD001163 | Pride
Plasmodium Proteomics Gametogenesis Male gametes 
ProteomicsProteomics of Human Skeletal Muscle
The skeletal muscle proteomics study of vastus lateralis muscle biopsies which were collected from participants from the Genetic and Epigenetic Study of Aging and Laboratory Testing (GESTALT). The participants were free of major diseases, except for controlled hypertension or a history of cancer tha...
ORGANISM(S): Homo sapiens (Human) 
2019-11-14 | PXD011967 | Pride
Proteomics Skeletal muscle 
ProteomicsRestoration of energy homeostasis by SIRT6 extends healthy lifespan
Aging leads to a gradual decline in physical activity and disrupted energy homeostasis. The NAD+-dependent SIRT6 deacylase regulates aging and metabolism through mechanisms that largely remain unknown. Here, we show that SIRT6 overexpression leads to a reduction in frailty and lifespan extension in ...
ORGANISM(S): Mus musculus (Mouse) 
2021-03-11 | PXD021447 | Pride
Glucose homeostasis Aging Gluconeogenesis Multi-omics Sirt6 
ProteomicsProteomics of Human Skeletal Muscle
The skeletal muscle proteomics study of vastus lateralis muscle biopsies which were collected from participants from the Genetic and Epigenetic Study of Aging and Laboratory Testing (GESTALT). The participants were free of major diseases, except for controlled hypertension or a history of cancer tha...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-10-17 | MSV000096122 | MassIVE
ProteomicsSkeletal Muscle Proteomics of High Functioning Octogenarians
Skeletal muscle mass and function decline more precipitously after the age 75 y. To provide insights into biologically relevant mechanisms for preserving muscle mass and physical function in advanced age, a battery of physical function tests, muscle cross-sectional area by MRI and a vastus lateralis...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000086195 | MassIVE
OtherA bioinformatics approach for integrated transcriptomic and proteomic comparative analyses of model and non-sequenced anopheline vectors of human malaria parasites
PXD ID: PXD000062, experiment: GambiaeOG3, data file: gambiaef11.mzxml. Data published as part of Mol Cell Proteomics. 2012 Oct 17 .From the Abstract: {{i}}... Plasmodium parasites are transmitted by Anopheles mosquitoes and the critical site of interaction is at the mosquito"s luminal midgut brush...
ORGANISM(S): Mosquito 
GPM11210007339 | GPMDB
Resource Reanalysis 
ProteomicsHuman skin fibroblast proteome in healthy aging
The changes in the proteome of different human tissues with advancing age are poorly characterized. Here, we studied the proteins present in skin fibroblasts collected from 82 healthy individuals across a wide age spectrum (22 to 89 years old) who participated in the GESTALT (Genetic and Epigenetic...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-11-17 | MSV000088401 | MassIVE
ProteomicsP.falciparum - Whole organism, Dd2, SC (Tao,mcp,2014)
abundance based on Spectral counting, Dd2, Interaction consistency score: 2.8, Coverage: 81
ORGANISM(S): 5833 
2014-00-00 | 3453092459 | PAXDB
ProteomicsP.falciparum - Whole organism, Girbc, SC (Tao,mcp,2014)
abundance based on Spectral counting, GiRBC, Interaction consistency score: 2.9, Coverage: 88
ORGANISM(S): 5833 
2014-00-00 | 3294826571 | PAXDB
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