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ProteomicsThe ER-embedded UBE2J1/RNF26 ubiquitylation complex in spatio-temporal control of the endolysosomal pathwayThe ER-embedded UBE2J1/RNF26 ubiquitylation complex in spatio-temporal control of the endolysosomal pathway
The endolysosomal system fulfills a wide variety of cellular functions, many of which are modulated through interactions with other organelles. In particular, the ER exerts spatiotemporal constraints on the organization and motility of endosomes and lysosomes. We have recently described the ER trans...
ORGANISM(S): Homo sapiens (Human) 
2021-01-22 | PXD022104 | Pride
Endoplasmic reticulum Endosomes Ubiquitin Rnf26 Egfr Ube2j1 
GenomicsMicroarray of HEK293-PIGS-KO and HEK293-PIGS-UBE2J1-DKO cells.
Microarray of HEK293-PIGS-KO and HEK293-PIGS-UBE2J1-DKO cells.
PRJNA591166 | ENA
TranscriptomicsMicroarray of HEK293-PIGS-KO and HEK293-PIGS-UBE2J1-DKO cells.
Transcriptome analysis of total RNA samples from HEK293-PIGS-KO and HEK293-PIGS-UBE2J1-DKO cells. To check whether KO of UBE2J1 upregulates genes of GPI biosthesis pathway, we used microarrays to analyze gene expression change by KO of UBE2J1 and comfirmed that known GPI pathway genes are not change...
ORGANISM(S): Homo sapiens 
2020-01-08 | GSE140855 | GEO
UnknownUBE2J1 inhibits colorectal cancer progression by promoting ubiquitination and degradation of RPS3.
Not available
S-EPMC9957728 | biostudies-literature
GenomicsUBE2J1 is the E2 Ubiquitin Conjugating Enzyme Required for Androgen Receptor Degradation
UBE2J1 is the E2 Ubiquitin Conjugating Enzyme Required for Androgen Receptor Degradation
PRJNA1003118 | ENA
UnknownZfx-induced upregulation of UBE2J1 facilitates endometrial cancer progression via PI3K/AKT pathway.
Not available
S-EPMC8043169 | biostudies-literature
UnknownThe E2 ubiquitin-conjugating enzyme UBE2J1 is required for spermiogenesis in mice.
Not available
S-EPMC4263858 | biostudies-literature
UnknownUbiquitin-conjugating enzyme UBE2J1 negatively modulates interferon pathway and promotes RNA virus infection.
Not available
S-EPMC6114777 | biostudies-literature
UnknownUBE2J1 knockdown promotes cell apoptosis in endometrial cancer via regulating PI3K/AKT and MDM2/p53 signaling.
Not available
S-EPMC9961967 | biostudies-literature
UnknownThe role of ubiquitin-conjugating enzyme Ube2j1 phosphorylation and its degradation by proteasome during endoplasmic stress recovery.
Not available
S-EPMC5559397 | biostudies-literature
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