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TranscriptomicsEvidence for a key role of cytochrome bo3 oxidase in respiratory energy metabolism of Gluconobacter oxydans
The obligatory aerobic acetic acid bacterium Gluconobacter oxydans oxidizes a variety of substrates in the periplasm by membrane-bound dehydrogenases, which transfer the reducing equivalents to ubiquinone. Two quinol oxidases, cytochrome bo3 and cytochrome bd, then catalyze transfer of the electrons...
ORGANISM(S): Gluconobacter oxydans 621H 
2013-07-26 | E-GEOD-47782 | biostudies-arrayexpress
TranscriptomicsIdentification of LPS-inducible genes down-regulated by ubiquinone in human THP-1 cells
Coenzyme Q10 (CoQ10) is an obligatory element in the respiratory chain and functions as a potent antioxidant of lipid membranes. More recently, anti-inflammatory effects as well as an impact of CoQ10 on gene expression have been observed. To reveal putative effects of Q10 on LPS-induced gene express...
ORGANISM(S): Homo sapiens 
2010-12-22 | E-GEOD-19625 | biostudies-arrayexpress
MetabolomicsTerminalia chebula decoction-processed Aconitum kusnezoffii preserves therapeutic effects through regulation of metabolism and intestinal microbiota

Background: Aconitum kusnezoffii Reichb. is a commonly used medicinal herb in Mongolian medicine, a branch of traditional Chinese medicine. Processing A. kusnezoffii with a decoction of Terminalia chebula Retz. represents a characteristic and widely applied detoxification method in Mongolian medi...

2026-06-27 | MTBLS14867 | MetaboLights
UnknownElucidation of roles for vitamin B12 in regulation of folate, ubiquinone, and methionine metabolism.
Not available
S-EPMC5320969 | biostudies-literature
UnknownA genome-wide screen in Escherichia coli reveals that ubiquinone is a key antioxidant for metabolism of long-chain fatty acids.
Not available
S-EPMC5723998 | biostudies-literature
UnknownComplex II subunit SDHD is critical for cell growth and metabolism, which can be partially restored with a synthetic ubiquinone analog.
Not available
S-EPMC8196461 | biostudies-literature
MetabolomicsClostridium butyricum ameliorates meat quality in coccidiosis-affected sheep by rescuing thiamine diphosphate-mediated glucose metabolism

Sheep coccidiosis, caused by Eimeria spp., is widely studied for inducing diarrhea, but its impact on mutton quality remains poorly understood. Here, we systematically investigated the effects of Eimeria infection on meat quality and the interventing role of Clostridium butyri...

2026-04-27 | MTBLS14093 | MetaboLights
TranscriptomicsCodY in Staphylococcus aureus: regulatory link between metabolism and virulence gene expression
CodY is a conserved regulator in gram-positive organisms described to repress metabolic genes mainly involved in nitrogen metabolism but also to control the expression of virulence genes in pathogens. We constructed codY gene-replacement mutants in three unrelated S. aureus strains (Newman, UAMS-1, ...
ORGANISM(S): Staphylococcus aureus subsp. aureus USA300 
2008-11-06 | E-GEOD-12340 | biostudies-arrayexpress
MetabolomicsMitochondrial metabolism sustains DNMT3A-R882-mutant clonal haematopoiesis
Somatic DNMT3A R882 codon mutations drive the most common form of clonal haematopoiesis (CH) and are associated with increased acute myeloid leukaemia (AML) risk1,2. Preventing expansion of DNMT3A-R882-mutant haematopoietic stem/progenitor cells (HSPCs) may therefore avert progression to AML. To ide...
2025-02-06 | MTBLS12201 | MetaboLights
UnknownSelenium reduction of ubiquinone via SQOR suppresses ferroptosis.
Not available
S-EPMC11694790 | biostudies-literature
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