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TranscriptomicsTranscription profiling of human airway epithelium, large airways, phenotypically normal smokers vs non-smokers, MAS5 (HuGeneFL)
Upregulation of Expression of the Ubiquitin Carboxyl Terminal Hydrolase L1 Gene in Human Airway Epithelium of Cigarette Smokers; The microarray data deposited here is from 44 HuGeneFL GeneChips, from 9 normal non-smokers and 13 phenotypic normal smokers, large airways, 2 samples per individual, one ...
ORGANISM(S): Homo sapiens 
2008-11-07 | E-GEOD-5056 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human airway epithelium, large airways, from phenotypically normal smokers vs non-smokers
Upregulation of Expression of the Ubiquitin Carboxyl Terminal Hydrolase L1 Gene in Human Airway Epithelium of Cigarette Smokers; The microarray data deposited here is from 11 HG-U133A GeneChips, from 5 normal non-smokers and 6 phenotypic normal smokers, large airways. Samples from the small airways ...
ORGANISM(S): Homo sapiens 
2009-04-25 | E-GEOD-5057 | biostudies-arrayexpress
ProteomicsCovalent Fragment Screening and Optimization Identifies Chloroacetohydrazide Scaffold as Inhibitors for Ubiquitin C- terminal Hydrolase L1
Dysregulation of the ubiquitin-proteasome systems is a hallmark of various disease states including neurodegenerative diseases and cancer. Ubiquitin C-terminal Hydrolase L1 (UCHL1), a deubiquitinating enzyme, is expressed primarily in the central nervous system under normal physiological conditions,...
ORGANISM(S): Homo sapiens (Human) 
2026-10-09 | PXD045257 | Pride
Breast cancer Covalent inhibitor Deubiquitinating enzyme Chloroacetohydrazide Uchl1 Chloroacetamide Ubiquitin c-terminal hydrolase l1 Dub Probe discovery 
UnknownUbiquitin C-Terminal Hydrolase L1 regulates myoblast proliferation and differentiation.
Not available
S-EPMC5584584 | biostudies-literature
UnknownUbiquitin C-terminal hydrolase L1 (UCH-L1): structure, distribution and roles in brain function and dysfunction.
Not available
S-EPMC4980807 | biostudies-literature
UnknownNon-functional ubiquitin C-terminal hydrolase L1 drives podocyte injury through impairing proteasomes in autoimmune glomerulonephritis.
Not available
S-EPMC10102022 | biostudies-literature
GenomicsUbiquitin C-terminal hydrolase isozyme L1 (UCHL1) is associated with shelterin complex at interstitial telomeric sites
Ubiquitin C-terminal hydrolase isozyme L1 (UCHL1) is primarily expressed in neuronal cells and neuroendocrine cells. It is a multifunctional protein involved in deubiquitination, ubiquitination, and ubiquitin homeostasis. UCHL1 has been associated with various diseases, including many cancers, but i...
ORGANISM(S): Homo sapiens 
2018-02-23 | GSE97111 | GEO
UnknownThe requirement of ubiquitin C-terminal hydrolase L1 in mouse ovarian development and fertility†.
Not available
S-EPMC9382372 | biostudies-literature
UnknownUbiquitin C-terminal hydrolase-L1 protects cystic fibrosis transmembrane conductance regulator from early stages of proteasomal degradation.
Not available
S-EPMC2857010 | biostudies-literature
UnknownUbiquitin C-terminal hydrolase L1 (UCH-L1) loss causes neurodegeneration by altering protein turnover in the first postnatal weeks.
Not available
S-EPMC6475369 | biostudies-literature
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