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The proteasome recognizes target proteins that have been covalently marked by ubiquitin chains. The ubiquitin signal is subject to rapid editing at the proteasome, allowing it to reject substrates based on topological features of their attached ubiquitin chains. Editing is mediated by a key regulato...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-02-22 | PXD029402 | Pride
Disomes and Disomes ubp6∆ vs. wild-type
Transcriptional profiling of anreuploid yeast strains grown in rich medium YEPD
ORGANISM(S): Saccharomyces cerevisiae Saccharomyces cerevisiae W303 
2014-02-20 | GSE55166 | GEO
Aneuploidy causes a proliferative disadvantage in all cells analyzed to date, yet this condition is associated with a disease characterized by unabated proliferative potential, cancer. The mechanisms that allow cancer cells to tolerate the adverse effects of aneuploidy are not known. To probe this q...
ORGANISM(S): Saccharomyces cerevisiae 
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