Sort   by:  
 Page size 
GenomicsAlteration of gene expression in ubr-5(-) and pabp-2(RNAi)
Alteration of gene expression in ubr-5(-) and pabp-2(RNAi)
PRJNA1089166 | ENA
ProteomicsLoss of the E3 ubiquitin ligases UBR-5 or HECD-1 restores Caenorhabditis elegans development in the absence of SWI/SNF function
SWItch/Sucrose Non-Fermenting (SWI/SNF) complexes are a family of chromatin remodellers that are conserved across eukaryotes. Mutations in subunits of SWI/SNF cause a multitude of different developmental disorders in humans, most of which have no current treatment options. Here we identify an alanin...
ORGANISM(S): Caenorhabditis elegans 
2023-01-24 | PXD037497 | Pride
Hecd-1 Ubr-5 Development Swi/snf Ubiquitination Ubr5 Hectd1 C. elegans 
TranscriptomicsAlteration of gene expression in ubr-5(-) and pabp-2(RNAi)
To investigate how UBR-5 and PABP-2 affect gene expression profile, we generated ubr-5(-) c elegans mutant and performed RNA seq in combination with pabp-2(RNAi).
ORGANISM(S): Caenorhabditis elegans 
2024-09-30 | GSE261826 | GEO
UnknownUBR-5, a Conserved HECT-Type E3 Ubiquitin Ligase, Negatively Regulates Notch-Type Signaling in Caenorhabditis elegans.
Not available
S-EPMC4938665 | biostudies-literature
UnknownUBR-5 and UBE2D mediate timely exit from stem fate via destabilization of poly(A)-binding protein PABP-2 in cell state transition.
Not available
S-EPMC11513905 | biostudies-literature
UnknownLoss of the E3 ubiquitin ligases UBR-5 or HECD-1 restores Caenorhabditis elegans development in the absence of SWI/SNF function.
Not available
S-EPMC9945973 | biostudies-literature
GenomicsMNase-seq facilitates quantitative analysis of nucleosome positioning of wild type and mutant SWI/SNF complexes
Purpose: The goal of this study is to evaluate potentially direct targets of altered chromatin remodeller SWI/SNF on nucleosome positioning at gene promoters by means of MNase-sequencing from synchronised L1-staged swsn‑1 single mutant, swsn‑1; snfc‑5 double mutants, swsn‑1; snfc‑5; ubr‑5 triple mut...
ORGANISM(S): Caenorhabditis elegans 
2023-01-01 | GSE218808 | GEO
UnknownUBR7 functions with UBR5 in the Notch signaling pathway and is involved in a neurodevelopmental syndrome with epilepsy, ptosis, and hypothyroidism.
Not available
S-EPMC7820726 | biostudies-literature
GenomicsMNase-seq facilitates quantitative analysis of nucleosome positioning of wild type and mutant SWI/SNF complexes
MNase-seq facilitates quantitative analysis of nucleosome positioning of wild type and mutant SWI/SNF complexes
PRJNA905658 | ENA
Genomics
Ribonanza chemical mapping libraries, Jan 2024
PRJNA1077399 | ENA
Sort   by:  
 Page size