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ProteomicsBoxCar and Shotgun Proteomic Analyses Reveal Molecular Networks Regulated by UBR5 in Prostate Cancer
The project aims to compare BoxCar and shotgun proteomics in identifying proteins regulated by UBR5 in prostate cancer cells.
ORGANISM(S): Homo sapiens (Human) 
2022-02-22 | PXD026382 | Pride
Xrcc3 Proteomics Prostate cancer Network Boxcar Shotgun Ubr5 Fancd2 
ProteomicsUBR5 in B cell development TMT
Coordination of a number of molecular mechanisms including transcription, alternative splicing, and class switch recombination are required to facilitate development, activation, and survival of B cells. Disruption of these pathways can result in malignant transformation. Recently, next generation s...
ORGANISM(S): Mus musculus (Mouse) 
2020-11-19 | PXD014307 | Pride
Tmt ubr5 bcells spleen mouse 
ProteomicsUBR5 Forms Ligand-Dependent Complexes on Chromatin to Regulate Nuclear Hormone Receptor Stability
Nuclear hormone receptors (NRs) are ligand-binding transcription factors that are widely targeted therapeutically. Hormone binding triggers NR activation and their subsequent proteasomal degradation through unknown ligand-dependent ubiquitin ligase machinery. NR degradation is therapeutically releva...
ORGANISM(S): Homo sapiens (Human) 
2023-07-20 | PXD040953 | Pride
Nuclear receptors Ubr5 Degradation Hormones Chromatin 
GenomicsEffect of TRIP12, UBR5, or HOIP in gene expression
Effect of TRIP12, UBR5, or HOIP in gene expression
PRJNA1209928 | ENA
GenomicsRNA-seq for UBR5-regulated genes in tumor associated macrophages
RNA-seq for UBR5-regulated genes in tumor associated macrophages
PRJNA666933 | ENA
ProteomicsUBR5 Forms Ligand-Dependent Complexes on Chromatin to Regulate Nuclear Hormone Receptor Stability
Nuclear hormone receptors (NRs) are ligand-binding transcription factors that are widely targeted therapeutically. Hormone binding triggers NR activation and their subsequent proteasomal degradation through unknown ligand-dependent ubiquitin ligase machinery. NR degradation is therapeutically releva...
ORGANISM(S): Homo sapiens (Human) 
2023-07-20 | PXD041749 | Pride
Nuclear receptors Ubr5 Degradation Hormones Chromatin 
GenomicsUBR5 promotes antiviral immunity by disengaging the transcriptional brake on RIG-I like receptors
UBR5 promotes antiviral immunity by disengaging the transcriptional brake on RIG-I like receptors
PRJNA1029049 | ENA
GenomicsUBR5 Mediates Menin Inhibitor Dependent Menin/KMT2A Complex Stability [ChIP-seq]
UBR5 Mediates Menin Inhibitor Dependent Menin/KMT2A Complex Stability [ChIP-seq]
PRJNA1272575 | ENA
GenomicsUBR5 Mediates Menin Inhibitor Dependent Menin/KMT2A Complex Stability [RNA-seq]
UBR5 Mediates Menin Inhibitor Dependent Menin/KMT2A Complex Stability [RNA-seq]
PRJNA1272588 | ENA
GenomicsQuantitative Analysis of Transcriptomes between Negative control, UBR5 depleted and MYC depleted HeLa cells
Quantitative Analysis of Transcriptomes between Negative control, UBR5 depleted and MYC depleted HeLa cells
PRJNA600869 | ENA
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