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ProteomicsProximity labelling identification of ULK1 wild-type (WT) and ULK1-K46I (kinase dead) interactors upon mitochondria tethering in U2OS WT cells
This project involved generating three stable cell lines using a Flp-In system, each containing specific integrated constructs: "FKBPx2-myc-APEX2-ULK1", "FKBPx2-myc-APEX2-ULK1-K46I" (kinase-dead mutant), and "FKBPx2-myc-APEX2" (control). All cell lines additionally express an outer mitochondrial mem...
ORGANISM(S): Homo sapiens (Human) 
2026-04-24 | PXD068381 | Pride
Mitophagy Autophagy Ulk1-k46i Ulk1 Proximity labeling Apex2 
UnknownPhosphorylation of ULK1 by AMPK is essential for mouse embryonic stem cell self-renewal and pluripotency.
Not available
S-EPMC5833692 | biostudies-literature
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