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UnknownUltrasensitive proteome analysis using paramagnetic bead technology.
Not available
S-EPMC4299378 | biostudies-literature
ProteomicsUltrasensitive proteomics depicted an in-depth landscape for the very early stage of mouse maternal-to-zygotic transition
Maternal-to-zygotic transition (MZT) is a conserved and fundamental process during which the maternal environment of oocyte transits to the zygotic genome driven expression program, and terminally differentiated oocyte and sperm are reprogrammed to totipotency. Metaphase II (MII) oocytes and zygotes...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-23 | PXD041399 | Pride
Mouse maternal-to-zygotic transition One-cell embryo Metaphase ii (mii) oocyte Ultrasensitive proteome technology 
UnknownUltrasensitive proteomics depicted an in-depth landscape for the very early stage of mouse maternal-to-zygotic transition.
Not available
S-EPMC10499587 | biostudies-literature
ProteomicsHarnessing PROTAC technology to combat stress hormone receptor activation
We want to quantify the proteome alteration following PROTAC mediated Glucocorticoid receptor depletion in vitro.
ORGANISM(S): Homo sapiens (Human) 
2023-12-11 | PXD046949 | Pride
Gr protac A549 Lc-ms/ms 
ProteomicsAutomated mass spectrometry imaging of over 2000 proteins from tissue sections at 100-um spatial resolution
Imaging mass spectrometry is a powerful emerging tool for mapping the spatial distribution of biomolecules across tissue surfaces. Here the authors showcase an automated technology for deep proteome imaging that utilizes ultrasensitive microfluidics and a mass spectrometry workflow to analyze tissue...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2019-10-04 | MSV000084421 | MassIVE
ProteomicsComparative proteomic landscapes provide insights into mammalian preimplantation development
Proteins play a crucial role in the central dogma as the end product of gene expression. However, a deep proteomic landscape is still the missing puzzle piece of the comprehensive understanding of mammalian preimplantation development. Here, using our recently developed Comprehensive Solution of Ult...
ORGANISM(S): Mus musculus (Mouse) 
2025-11-27 | PXD043363 | Pride
Protein turnover Mouse preimplantation development Multi-omics analysis Zygotic genome activation (zga) Ultrasensitive proteomics Cross species analysis 
ProteomicsUltra-sensitive proteomics using second generation micro pillar array LC technology with Orbitrap Exploris™ 480 and FAIMS
In the light of the ongoing single-cell revolution, scientific disciplines are combining forces with the ultimate goal to retrieve as much relevant data as possible from trace amounts of biological material. For single cell proteomics, this implies optimizing the entire workflow from initial cell is...
ORGANISM(S): Homo sapiens (Human) 
2021-06-28 | PXD024017 | Pride
Micro pillar Low-input proteomics Single sell proteomics 
ProteomicsComparative proteomic landscapes provide insights into mammalian preimplantation development and failure
Understanding mammalian preimplantation development, particularly in humans, at the proteomic level remains limited. Here, we applied our comprehensive solution of ultrasensitive proteomic technology to measure the proteomic profiles of oocytes and early embryos and identified nearly 8,000 proteins ...
ORGANISM(S): Mus musculus (Mouse) 
2025-02-05 | PXD054371 | Pride
Protein turnover Mouse preimplantation development Multi-omics analysis Zygotic genome activation (zga) Ultrasensitive proteomics Cross species analysis 
ProteomicspSILAC-SP3 of RGC axonal growth cones
To form operative neuronal networks neurons connect to their synaptic partners by axonal outgrowth guided by the movement of the axon tip, a specialized structure known as the growth cone (GC), which travels along stereotypical paths by sensing extracellular guidance cues. Interestingly, GCs contain...
ORGANISM(S): Xenopus laevis (African clawed frog) 
2018-08-10 | PXD005469 | Pride
Axon Psilac 
UnknownAccelerated chromatin biochemistry using DNA-barcoded nucleosome libraries.
Not available
S-EPMC4130351 | biostudies-literature
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