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UnknownSelective profiling of ribosomes associated with yeast Upf proteins.
Not available
S-EPMC6387845 | biostudies-literature
MetabolomicsIdentification and validation of poly-metabolite scores for diets high in ultra-processed food: An observational study and post-hoc randomized controlled crossover-feeding trial.

BACKGOUND: Ultra-processed food (UPF) accounts for a majority of calories consumed in the United States, but the impact on human health remains unclear. We aimed to identify poly-metabolite scores in blood and urine that are predictive of UPF intake.

METHODS AND FIN...

2025-07-12 | MTBLS12705 | MetaboLights
UnknownSensing of H2O2-induced oxidative stress by the UPF factor complex is crucial for activation of catalase-3 expression in Neurospora.
Not available
S-EPMC10578600 | biostudies-literature
ProteomicsRibosome-bound Upf1 forms distinct 80S complexes and conducts mRNA surveillance
Upf1, Upf2, and Upf3 are the central regulators of nonsense-mediated mRNA decay (NMD), the eukaryotic mRNA quality control pathway generally triggered when a premature termination codon is recognized by the ribosome. The NMD-related functions of the Upf proteins likely commence while these factors a...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-10-21 | PXD029577 | Pride
Upf proteins Nmd substrates Ribosome Selective ribosome profiling 
UnknownA competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decay.
Not available
S-EPMC2689706 | biostudies-literature
TranscriptomicsRibosome-bound Upf1 forms distinct 80S complexes and conducts mRNA surveillance
Upf1, Upf2, and Upf3 are the central regulators of nonsense-mediated mRNA decay (NMD), the eukaryotic mRNA quality control pathway generally triggered when a premature termination codon is recognized by the ribosome. The NMD-related functions of the Upf proteins likely commence while these factors a...
ORGANISM(S): Saccharomyces cerevisiae 
2022-10-21 | GSE186795 | GEO
ProteomicsProteomic Investigation of the Neuroprotective and Anti-Inflammatory Effects of Undaria pinnatifida Fucoidan In Vivo
Undaria pinnatifida fucoidan (UPF), a bioactive sulphated polysaccharide, has been widely recognised for its anti-inflammatory, antioxidant, antitumor, anticoagulant, antiviral, and immunomodulatory properties. However, the precise mechanisms through which UPF regulates systemic inflammation, oxidat...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-29 | PXD060861 | Pride
Fucoidans  undaria pinnatifida  inflammation  oxidative stress  neuroprotection  proteomic analysis  gut microbiome  enterobacteriales  tnf-α  il-1β  il-6 
ProteomicsThe high mobility group protein HMG20A cooperates with the histone reader PHF14 to modulate cancer signaling pathways.
High mobility group proteins are chromatin regulators with essential functions in development, cell differentiation and cell proliferation. The protein HMG20A contains three well defined domains: an amino terminal intrinsically distorted domain, a high mobility group box with higher affinity for dou...
ORGANISM(S): Homo sapiens (Human) 
2022-10-13 | PXD030769 | Pride
Cancer High mobility group proteins 
ProteomicsProteomic profile of plasma-derived extracellular vesicles from Colombian pregnant women with Plasmodium-soil transmitted helminths coinfection
Background: Knowledge about extracellular vesicles (EV) and their molecular cargo in gestational parasitic infections, particularly by Plasmodium and soil-transmitted helminths (STH), is almost non-existent. Objective: To perform isolation and molecular characterization of plasma-derived EVs fro...
ORGANISM(S): Homo sapiens (Human) 
2024-11-26 | PXD051270 | Pride
Helminths Extracellular vesicles Plasmodium Lc-msms 
UnknownSpatial control of lipid droplet proteins by the ERAD ubiquitin ligase Doa10.
Not available
S-EPMC4969576 | biostudies-literature
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