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Unicellular eukaryotes and helminths Targeted loci environmental
Background: Knowledge about extracellular vesicles (EV) and their molecular cargo in gestational parasitic infections, particularly by Plasmodium and soil-transmitted helminths (STH), is almost non-existent. Objective: To perform isolation and molecular characterization of plasma-derived EVs fro...
ORGANISM(S): Homo sapiens (Human) 
2024-11-26 | PXD051270 | Pride
B cell fate mapping reveals their contribution to the memory immune response against helminths
To identify B cell memory in the response against helminths we used a fate-mapping aproach using inducible Cre to label B cells participating in the immune response against Nippostrongylus brasiliensis. We transferred our marked cells into wild-type recipient mice and compared the cells before and a...
ORGANISM(S): Mus musculus 
2022-11-15 | GSE209523 | GEO
Maternal Helminths Rewire the Microbiota to Promote Offspring Antiviral Immunity via Indole-3-Propionic Acid
Maternal environmental exposures are critical in shaping offspring immunity. Yet, the role of helminths, mammals’ symbiotic evolutionary partners that have been eliminated from modern societies, remains poorly understood. Here, we show that maternal helminth infection enhances type I interferon (IFN...
ORGANISM(S): Mus musculus 
2026-07-01 | GSE299495 | GEO
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