Upstream regulator.

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Unknown (3593)
Genomics (961)
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Organisms

Homo sapiens (404)
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synthetic construct (7)
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Beauveria bassiana ARSEF 2860 (1)

Organisms

Homo sapiens (250)
Mus musculus (201)
Drosophila melanogaster (24)
Danio rerio (15)
Arabidopsis thaliana (15)
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Rattus norvegicus (11)
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Thermothelomyces thermophilus ATCC 42464 (2)
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Technology Type

Mass Spectrometry (75)
Shotgun proteomics (42)
Bottom-up proteomics (13)
Affinity purification coupled with mass spectrometry proteomics (12)
Data-dependent acquisition (10)
Mass spectrometry (5)
Gel-based experiment (5)
SWATH MS (4)
Mass spectrometry assay (2)
Data-independent acquisition (2)
Top-down proteomics (2)
Illumina HiSeq 2000 (1)
Chemical cross-linking coupled with mass spectrometry proteomics (1)
HDMSE (1)

Instrument Platform

NextSeq 500 (10)
Illumina HiSeq 2000 (8)
Illumina NovaSeq 6000 (5)
Illumina HiSeq 2500 (4)
Q Exactive (4)
DNA Microarray Scanner BA [Agilent Technologies] (2)
Illumina HiSeq 1500 (2)
Illumina HiSeq 4000 (2)
Orbitrap Fusion Lumos (2)
TimsTOF fleX (2)
Liquid Chromatography MS - negative - hilic (2)
I686 (1)
Agilent DNA Microarray Scanner Model #G2565BA (1)
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Computater Servers UPPMAX-SNIC. (1)
Illumina Tru-seq RNA (1)
NanoDrop spectrophotometer (NanoDrop Technologies, Wilmington, DE) (1)
Dynamic light scattering and zeta potential. The experiments were performed on a Malvern Zetasizer NanoZS instrument using a He-Ne laser (Max, 5 mW) at 633 nm. (1)
ScanArray 5000 [PerkinElmer] (1)
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Instrument (1)
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Publication Date

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2010 (73)
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2014 (69)
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2020 (63)
2013 (63)
2012 (60)
2015 (57)
2019 (51)
2016 (51)
2011 (46)
2017 (42)
2018 (31)
2009 (23)
2008 (22)
2007 (19)
2005 (13)
2006 (6)
2004 (1)
2003 (1)

UNIPROT ID/AC

Q13153 (1)
P78527 (1)
P49137 (1)
P49815 (1)
Q92574 (1)
P23443 (1)
P42336 (1)
P35568 (1)
P01308 (1)
Q96B36 (1)
P42345 (1)
P06213 (1)
P27986 (1)
Q13315 (1)
P31749 (1)
5811.TGME49_002070 (1)
5811.TGME49_002130 (1)
5811.TGME49_002690 (1)
5811.TGME49_003210 (1)
5811.TGME49_003530 (1)
5811.TGME49_004050 (1)
5811.TGME49_004530 (1)
5811.TGME49_005130 (1)
5811.TGME49_005250 (1)
5811.TGME49_008350 (1)
5811.TGME49_008590 (1)
5811.TGME49_008730 (1)
5811.TGME49_009060 (1)
5811.TGME49_009100 (1)
5811.TGME49_009760 (1)

CHEBI ID

CHEBI:27823 (3)
CHEBI:17750 (3)
CHEBI:18050 (3)
CHEBI:18019 (3)
CHEBI:16015 (3)
CHEBI:16335 (3)
CHEBI:15603 (3)
CHEBI:16643 (3)
CHEBI:17295 (3)
CHEBI:180914 (2)
CHEBI:120 (2)
CHEBI:137259 (2)
CHEBI:74754 (2)
CHEBI:74800 (2)
CHEBI:74753 (2)
CHEBI:16231 (2)
CHEBI:28189 (2)
CHEBI:17057 (2)
CHEBI:15811 (2)
CHEBI:17164 (2)
CHEBI:69081 (2)
CHEBI:74762 (2)
CHEBI:30754 (2)
CHEBI:40521 (2)
CHEBI:32365 (2)
CHEBI:18261 (2)
CHEBI:30849 (2)
CHEBI:16708 (2)
CHEBI:28621 (2)
CHEBI:506227 (2)

Metabolite Name

L-Lysine (5)
L-Norleucine (4)
Adenosine (4)
L-Leucine (4)
L-Phenylalanine (4)
L-Citrulline (3)
Betaine (3)
L-Asparagine (3)
L-Proline (3)
L-Arginine (3)
L-Glutamine (3)
Stachyose (3)
Thymidine (3)
L-Methionine (3)
Isoacteoside (2)
Ethyl 3-hydroxybutyrate (2)
Fraxidin (2)
Ile-Asn (2)
3-O-Feruloylquinic acid (2)
Laurocapram (2)
S-Methyl-5'-thioadenosine (2)
Vitamin K1 (2)
3-Ureidopropionate (2)
Baicalin (2)
S-Adenosylmethionine (2)
Pro-Glu (2)
Ile-Thr (2)
Leu-Asp (2)
Agmatine (2)
1-Monomyristin (2)

First Public Date

2026 (118)
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2014 (71)
2023 (63)
2022 (61)
2020 (58)
2019 (54)
2021 (49)
2018 (32)
2017 (26)
2015 (21)
2016 (17)
2013 (8)

Modelling Approach

Differential equation model (1)
Ordinary differential equation model (1)

Lab affiliation

Professor in Microbiology and Biochemistry School of Biomolecular and Biomedical Science https://www.ucd.ie/sbbs/ BiOrbic https://biorbic.com UCD O'Brien Centre for Science 4th Floor, room E4.09 University College Dublin Belfield D4, Ireland (2)
Baxter Laboratory for Stem Cell Biology Department of Microbiology & Immunology Stanford University School of Medicine (1)
Bioanalytical Mass Spectrometry Group, Max-Planck-Institute for Multidisciplinary Sciences, Germany; Bioanalytics, Department of Clinical Chemistry, University Medical Center Göttingen, Germany (1)
Bioheat and mass transfer laboratory, Med-X Research Institute, Shanghai Jiao Tong University (1)
Biological Mass Spectrometry Lab, Department of Translational Medicine (DiMeT), Center for Translational Research on Autoimmune & Allergic Diseases - CAAD - University of Piemonte Orientale, Corso Trieste 15/A, 28100, Novara, Italy (1)
Biotech Research and Innovation Centre, University of Copenhagen, Ole Maaløes Vej 5, Copenhagen 2200, Denmark (1)
Cancer Science Institute of Singapore (CSI), National University of Singapore (NUS) (1)
Center for Integrative Genomics, CIG, UNIL Sorge, CH1015 Lausanne, Switzerland (1)
Central European Institute of Technology, Masaryk University, Brno, Czech Republic National Centre for Biomolecular research, Masaryk University, Brno, Czech Republic (1)
Centre for Cancer Biomarkers CCBIO, Department of Clinical Medicine, Section for Pathology, University of Bergen, Bergen, N-5021, Norway Department of Pathology, Haukeland University Hospital, Bergen, N-5021, Norway (1)
Centre for Drug Safety Science, Dept Pharmacology and Therapeutics, Institute for Systems, Molecular and Integrative Biology, University of Liverpool (1)
Centre for Drug Safety Science, Dept Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool (1)
Chair in Metabolic Systems Biology, Charles Perkins Centre, The University of Sydney, Australia (1)
Core Facility for Mass Spectrometry & Proteomics Center for Molecular Biology of Heidelberg University Heidelberg, Germany (1)
DIVAS department of veterinary medicine and animal science (1)
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, United States (1)
Department of Biological Sciences Rutgers University Newark (1)
Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, K1H 8M5, Canada (1)
Department of Chemistry, Yale University West Campus Chemical Biology Institute (1)
Department of Medical Oncology and Department of Molecular Cancer Research, Cancer Genomics Netherlands, University Medical Center Utrecht, Utrecht, the Netherlands (1)
Department of Molecular biology, medical biochemistry and pathology, Faculty of Medicine, Laval University, Quebec, QC, Canada (1)
Department of Neurology, School of Medicine, Yale University, New Haven (CT), USA (1)
Department of Pharmacy, University ‘‘G. d’Annunzio’’ of Chieti-Pescara, Chieti, Italy (1)
Department of Translational Medicine, Lund University, Lund Sweden (1)
Department ogf Pharmacy, University "G. d'Annunzio", Chieti, Italy (1)
Dept. Cell Biology and Molecular Medicince, Rutgers-New Jersey Mediccal School, Newark NJ (1)
Dept. Molecular Microbiology John Innes Centre Norwich Research Park Norwich, UK (1)
Dept. of Pharmacology and Toxicology Univ. of TX Medical Branch Galveston, TX 77555 (1)
Division of Immunobiology, Cincinnati Children’s Hospital, Cincinnati, OH Department of Pediatrics, University of Cincinnati, Cincinnati OH Correspondence: (1)
Dr. Ulrich Blank Department chair and team leader Mast cells and Basophils in Inflammation and Remodeling Inserm U 1149 & CNRS ERL8252 Université Paris-Diderot Faculté de Médecine Site X. Bichat 16, rue Henri Huchard F-75870 Paris Cedex 18 FRANCE (1)

IsPrivate

False (2)

Submitter Keywords

Manuscript Accepted (1)

Classification

bacteria (35)
fungi (11)
protozoa (9)

Study type

Transcription profiling by array (233)
ChIP-seq (70)
RNA-seq of coding RNA (62)
ChIP-chip by tiling array (11)
Other (10)
ChIP-chip by array (9)
Unknown experiment type (7)
Methylation profiling by array (4)
RNA-seq of non coding RNA (4)
Human - One-color microarray (2)
Transcription profiling by tiling array (2)
Comparative genomic hybridization by array (2)
MicroRNA profiling by array (2)
RNA-seq of coding RNA from single cells (2)
Animal - One-color microarray (1)
Cell line - One-color microarray (1)
Animal - High-throughput sequencing (1)
Cell line - High-throughput sequencing (1)
Genotyping by array (1)
Transcription profiling by RT-PCR (1)
MicroRNA profiling by high throughput sequencing (1)
ATAC-seq (1)
Ribo-seq (1)
DNA-seq (1)
Proteomic profiling by array (1)
Methylation profiling by high throughput sequencing (1)

Release Date

2022 (283)
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2017 (220)
2015 (213)
2014 (186)
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2011 (154)
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2010 (147)
2008 (87)
2009 (74)
2007 (56)
2026 (53)
2006 (44)
2005 (44)
2001 (29)
2000 (27)
2004 (23)
2003 (23)
2002 (22)
1999 (21)
1998 (15)
1997 (1)

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Identification of ANXA1 as A Novel Upstream Negative Regulator of Notch1 Function in AML

Abnormal Notch1 expression has an important role in tumorigenesis. However, upstream control mechanisms for Notch1 are still insufficiently understood. Acute myeloid leukemia (AML) is one of the most common and lethal blood malignancies with limited possibilities for treatment. Thus, new therapeutic...

ORGANISM(S): Homo Sapiens

2024-10-03 | PXD056593 |

TBX2 a novel upstream regulator of labor

PRJNA555139 | ENA

The Campylobacter jejuni transcriptional regulator CosR plays a role in the oxidative and aerobic stress response and is important for bacterial survival in vivo

Campylobacter jejuni is the leading bacterial cause of human gastroenteritis worldwide. Despite stringent microaerobic growth requirements, C. jejuni is ubiquitous in the aerobic environment. C. jejuni must possess finely tuned regulatory systems to sense and adapt to external stimuli such as oxidat...

ORGANISM(S): Campylobacter jejuni

2012-01-23 | E-BUGS-119 | biostudies-arrayexpress

The global response regulator RegR controls expression of denitrification genes in Bradyrhizobium japonicum

Bradyrhizobium japonicum RegSR regulatory proteins belong to the family of two-component regulatory systems, and orthologs are present in many Proteobacteria where they globally control gene expression mostly in a redox-responsive manner. In this work, we have performed a transcriptional profiling o...

ORGANISM(S): Bradyrhizobium japonicum

2014-09-01 | E-GEOD-56668 | biostudies-arrayexpress

SOX4 is an upstream transcriptional regulator of FOXC1 in acute myeloid leukemia [MeDIP-seq]

PRJNA729508 | ENA

SOX4 is an upstream transcriptional regulator of FOXC1 in acute myeloid leukemia [ATAC-seq]

PRJNA729506 | ENA

SOX4 is an upstream transcriptional regulator of FOXC1 in acute myeloid leukemia [4C-seq]

PRJNA729509 | ENA

SOX4 is an upstream transcriptional regulator of FOXC1 in acute myeloid leukemia [RNA-seq]

PRJNA729505 | ENA

HNF4a acts as upstream functional regulator of intestinal Wnt3 and Paneth cell fate

PRJNA719384 | ENA