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ProteomicsMitochondrial proteomics investigation of a cellular model of impaired dopamine homeostasis, an early step in Parkinson's disease pathogenesis
Impaired dopamine homeostasis is an early event in the pathogenesis of Parkinson's disease. Generation of intracellular reactive oxygen species consequent to dopamine oxidation leads to mitochondrial dysfunction and eventually cell death. Alterations in the mitochondrial proteome due to dopamine exp...
ORGANISM(S): Homo sapiens (Human) 
2014-04-15 | PXD000838 | Pride
Dopamine  human proteome project  mitochondria  mpp+  parkinson's disease  respiratory chain  shotgun proteomics  mse 
ProteomicsColon cancer stem cell over-expressing TAp63α
p63, a member of p53 family, is transcribed in different variants, containing (TA) or lacking (N) the N-terminal transactivation domain. Although the proteins of p53 family share high sequence and structural similarities, distinct functions for p63 are emerging. Here we provided a quantitative prote...
ORGANISM(S): Homo sapiens (Human) 
2014-03-17 | PXD000768 | Pride
Lc-msms Stable isotope dimethyl labeling Colon cancer stem cells P63 
ProteomicsColon cancer stem cell over-expressing ΔNp63α
p63, a member of p53 family, is transcribed in different variants, containing (TA) or lacking (ΔN) the N-terminal transactivation domain. Although the proteins of p53 family share high sequence and structural similarities, distinct functions for p63 are emerging. Here we provided a quantitative prot...
ORGANISM(S): Homo sapiens (Human) 
2014-03-17 | PXD000769 | Pride
Lc-msms Stable isotope dimethyl labeling Colon cancer stem cells P63 
TranscriptomicsLamin A/C is required for SHSY5Y neuroblastoma cell differentiation and its expression is linked to a less malignant phenotype.
The main scientific objective of the project was to investigate whether Lamin A/C could be involved in neuroblastoma differentiation. Moreover, taking into account the significance of differentiation stage in the neuroblastoma tumor progression we have also studied a possible role of Lamin A/C in th...
ORGANISM(S): Homo sapiens 
2013-07-11 | E-GEOD-30677 | biostudies-arrayexpress
UnknownDifferential Diagnosis of Inflammatory Arthropathies by Musculoskeletal Ultrasonography: A Systematic Literature Review.
Not available
S-EPMC7221062 | biostudies-literature
UnknownPsA-Disk, a novel visual instrument to evaluate psoriatic arthritis in psoriatic patients: an Italian derma-rheuma multicentre study.
Not available
S-EPMC6535736 | biostudies-literature
ProteomicsMetaproteomic analysis of mouse gut microbiota in the early life: taxonomic, functional and quantitative analysis to evaluate breastfeeding modulation
Metaproteomic analysis of mouse gut microbiota in the early life: taxonomic, functional and quantitative analysis to evaluate breastfeeding modulation
ORGANISM(S): Bacteria (ncbitaxon:2) Mus Musculus (ncbitaxon:10090) 
2018-07-22 | MSV000082651 | MassIVE
ProteomicsSequential Fractionation Strategy Identifies Nine Missing Proteins in The Mitochondrial Proteome of Commonly Used Cell Lines
Identification of mitochondrial proteins with a bottom up approach after organelle enrichment and 1D PAGE separation for 5 different cell lines. The bands were cut and the proteins reduced, alkylated and digested with trypsin according to a conventional protocol. Acquisition were performed on the Or...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-05-28 | MSV000082409 | MassIVE
ProteomicsMetaproteomics investigation on the gut microbiota of children affected by Autism Spectrum Disorder
Metaproteomics investigation of the Gut Microbiota in young subjects with Autism Spectrum Disorders and their relatives
ORGANISM(S): Bacteria (ncbitaxon:2) 
2020-04-06 | MSV000085232 | MassIVE
ProteomicsStandardization of mitochondrial proteomics v2 NP
Comparison of the extraction performances of three different mitochondria enrichment protocols (differential centrifugation, sucrose gradient, a commercial kit based on surfactants) on ten different cell lines. Samples were analysed on several instrumental platforms. Mitochondrial pellets were lysed...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-07-14 | MSV000081329 | MassIVE
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