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UnknownUrinary glycoproteins associated with aggressive prostate cancer.
Not available
S-EPMC7667684 | biostudies-literature
ProteomicsDifferentially Expressed Glycoproteins in Pre- and Post-Digital Rectal Examination Urine Samples for Detecting Aggressive Prostate Cancer
Nonaggressive prostate cancer (NAG-PCa) with Gleason score of 6 is considered as a low-risk disease and does not require clinical interventions. However, current assessment of aggressiveness of PCa is invasive using needle biopsies. Urine is an appealing biospecimen for noninvasive detection of aggr...
ORGANISM(S): Homo sapiens (Human) 
2023-07-20 | PXD036468 | Pride
Digital rectal examination Glycoproteomics Mass spectrometry Aggressive prostate cancer Urinary glycoproteins 
UnknownComparing Urinary Glycoproteins among Three Urogenital Cancers and Identifying Prostate Cancer-Specific Glycoproteins.
Not available
S-EPMC8945184 | biostudies-literature
Proteomicsurinary glycopeptide profile differentiates early cardiorenal risk in subjects not meeting criteria for chronic kidney disease
Early diagnosis and treatment of chronic kidney disease (CKD) is a worldwide challenge. Albuminuria is defined as urinary albumin:creatinine ratio (ACR) ≥30 mg/g. Subjects with ACR values below this cut-off and preserved renal function are considered at no cardiorenal risk, but increased risk is est...
ORGANISM(S): Homo sapiens (Human) 
2025-06-02 | PXD049688 | Pride
Urine  glycopeptide  chronic kidney disease  early cardiorenal risk albuminuria 
ProteomicsDetection of N‑glycoprotein associated with IgA nephropathy in urine as a potential diagnostic biomarker using glycosylated proteomic analysis
The present study aimed to clarify the potential diagnosis value of the urinary N-glycoproteins using mass spectrometry (MS) analysis in patients with IgA nephropathy (IgAN).
ORGANISM(S): Homo sapiens (Human) 
2023-08-13 | PXD041151 | Pride
Ms-based proteomics Urine Iga nephropathy Glycoproteins Biomarkers 
ProteomicsExtended sialylated O-glycan repertoire of human urinary glycoproteins discovered and characterized using EThcD
These are human urine samples from 4 healthy individuals. Cys residues were carbamidomethylated, proteins were digested with trypsin. Sample preparation and some of the data interpretation was described in: Pap, A.; Klement, E.; Hunyadi-Gulyas, E.; Darula, Z.; Medzihradszky, K. F. Status Report on t...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-10-25 | MSV000083070 | MassIVE
ProteomicsComprehensive N-Glycomics Profiling of Urinary Extracellular Vesicles Identifies a Novel Biomarker Panel for Diagnosis of Bladder Cancer
Bladder cancer (BC) is the most common urologic malignancy, facing enormous diagnostic challenges.Urinary extracellular vesicles (EVs) is a particularly promising source for developing diagnostic markers for bladder cancer because of the direct contact between urine and bladder. We investigate bioma...
ORGANISM(S): Homo Sapiens 
2024-11-14 | PXD057882 |
UnknownDevelopment of Parallel Reaction Monitoring Assays for the Detection of Aggressive Prostate Cancer Using Urinary Glycoproteins.
Not available
S-EPMC8631583 | biostudies-literature
ProteomicsGlycomics and Glycoproteomics Reveal Distinct Oligomannose Carriers Across Bladder Cancer Stages
Aberrant glycosylation is a hallmark of cancer, offering opportunities to enhance clinical decision-making and enable precise targeting of cancer cells. Nevertheless, alterations in the bladder urothelial carcinoma (BLCA) N-glycome remain poorly characterized. Here, we used in situ N-deglycosylation...
ORGANISM(S): Homo sapiens (Human) 
2025-05-20 | PXD063671 | Pride
Bladder cancer  n-glycomics  n-glycoproteins 
UnknownDifferentially expressed glycoproteins in pre- and post-digital rectal examination urine samples for detecting aggressive prostate cancer.
Not available
S-EPMC10200066 | biostudies-literature
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