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GenomicsThe effects of wild-type Usp24 or catalytically inactive USP24 on EgfrL858R-driven lung tumor specimens.
The effects of wild-type Usp24 or catalytically inactive USP24 on EgfrL858R-driven lung tumor specimens.
PRJNA1186555 | ENA
ProteomicsUSP24 is an ISG15 cross-reactive deubiquitinase that mediates IFN-I production by de-ISGylating the RNA helicase MOV10
The interferon Stimulated Gene-15 (ISG15) is a ubiquitin-like modifier induced by type I Interferon (IFN-I) and plays a crucial role in the innate immune response against viral infections. ISG15 is conjugated to target proteins by an enzymatic cascade through a process called ISGylation. While USP18...
ORGANISM(S): Homo sapiens (Human) 
2026-05-13 | PXD055843 | Pride
Human Innate immunity Ubiquitomics Isg15 Immunology Usp24 
TranscriptomicsThe effects of wild-type Usp24 or catalytically inactive USP24 on EgfrL858R-driven lung tumor specimens.
Ubiquitin-specific peptidase 24 (USP24), a cysteine protease, functions as deubiquitinating enzyme that recognizes and removes ubiquitin from the target protein. USP24 is overexpressed in various cancers and regulates the stability of proteins involved in cancer metastasis, cancer stemness, and drug...
ORGANISM(S): Mus musculus 
2025-04-22 | GSE281983 | GEO
UnknownUSP24 promotes drug resistance during cancer therapy.
Not available
S-EPMC8408266 | biostudies-literature
UnknownUSP24 stabilizes bromodomain containing proteins to promote lung cancer malignancy.
Not available
S-EPMC7705756 | biostudies-literature
UnknownUSP24 promotes hepatocellular carcinoma progression by deubiquitinating and stabilizing YAP1.
Not available
S-EPMC12034148 | biostudies-literature
UnknownThe deubiquitinating enzyme USP24 is a regulator of the UV damage response.
Not available
S-EPMC4359050 | biostudies-literature
UnknownUSP24 upregulation stabilizes PKA-Cα to promote lipogenesis, inflammation, and fibrosis during MASH progression.
Not available
S-EPMC12125897 | biostudies-literature
UnknownWP1130 reveals USP24 as a novel target in T-cell acute lymphoblastic leukemia.
Not available
S-EPMC6415346 | biostudies-literature
UnknownUSP24 promotes autophagy-dependent ferroptosis in hepatocellular carcinoma by reducing the K48-linked ubiquitination of Beclin1.
Not available
S-EPMC11461744 | biostudies-literature
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