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GenomicsUnraveling the transcriptomic profile of utero-tubal lavage fluid of ovarian cancer patients
The majority of ovarian cancers are diagnosed at an advanced stage and have a high mortality rate. Current screening strategies fail to improve prognosis because markers of early stage disease are lacking. This medical need justifies the search for biomarkers enabling early detection of ovarian canc...
EGAS00001005498 | EGA
ProteomicsMicrovesicle Proteomic profiling of Uterine Liquid Biopsy for Ovarian Cancer Early Detection
High-grade ovarian cancer (HGOC) is the leading cause of mortality from gynecological malignancies, due to diagnosis at a metastatic stage. Current screening options fail to improve mortality due to the absence of early-stage-specific biomarkers. We postulated that a liquid biopsy, such as utero-tub...
ORGANISM(S): Homo sapiens (Human) 
2019-02-16 | PXD009655 | Pride
Ovarian cancer Q-exactive Microvesicles Utero-tubal lavage Lc-ms/ms Biomarker 
ProteomicsMicrovesicle Proteomic profiling of Uterine Liquid Biopsy for Ovarian Cancer Early Detection
High-grade ovarian cancer (HGOC) is the leading cause of mortality from gynecological malignancies, due to diagnosis at a metastatic stage. Current screening options fail to improve mortality due to the absence of early-stage-specific biomarkers. We postulated that a liquid biopsy, such as utero-tub...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-09-19 | MSV000084345 | MassIVE
Genomicsutero-tubal lavage RNA seq DAC
Data Access Committee EGAC00001002241
EGAC00001002241 | EGA
ProteomicsProteomic Signature for Detection of High Grade Ovarian Cancer in germline BRCA mutation carriers
There are currently no screening methods for high grade ovarian cancer (HGOC) that guarantee effective early detection for high risk women such as germline BRCA mutation carriers. Therefore, the standard-of-care remains risk reducing salpingo-oophorectomy (RRSO) around age 40. Proximal liquid biopsy...
ORGANISM(S): Homo sapiens (Human) 
2022-09-13 | PXD030390 | Pride
Liquid biopsies Biomarkers Brca Ovarian cancer Uterine lavage 
UnknownRNA biomarkers from proximal liquid biopsy for diagnosis of ovarian cancer.
Not available
S-EPMC8740458 | biostudies-literature
Genomics22dbb1f8-fd86-4691-a971-f2192cc9f6c8 - samples
mRNA capture seq of uterotubal lavage samples
EGAD00001007933 | EGA
UnknownMicrovesicle Proteomic Profiling of Uterine Liquid Biopsy for Ovarian Cancer Early Detection.
Not available
S-EPMC6495259 | biostudies-literature
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