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TranscriptomicsThe Transcriptome of Utricle Hair Cell Regeneration in the Avian Inner Ear
A comprehensive transcriptome profile of chicken utricle hair cell across a 7 days regenerative time course. Compare gene expression changes in chicken utricle treated with streptomycin to the control. A total of 60 samples were collected from 11 different time points. Each time point contains at le...
ORGANISM(S): Gallus gallus 
2014-04-29 | E-GEOD-57134 | biostudies-arrayexpress
TranscriptomicsExpression data from chick cochlea and utricle
Inner ear auditory and vestibular tissues differ in their responses to mechanical stimuli. Chick cochlea and utricle sensory epithelia were microdissected at E20-E21. RNA was extracted and cRNA hybridized to Affymetrix microarrays.
ORGANISM(S): Gallus gallus 
2012-01-01 | E-GEOD-32272 | biostudies-arrayexpress
ProteomicsComparison of control and Elmod1 knockout utricle extracts using tandem mass tagging
Elmod1 knockout mice develop a severe inner ear defect beginning at early postnatal ages. Cuticular plates of utricle hair cells were initially formed normally, then degenerated after postnatal day 5 (P5). Similarly, hair bundles initially were formed normally, but the cell’s apical membrane subsequ...
ORGANISM(S): Mus musculus (Mouse) 
2018-10-24 | PXD006164 | Pride
Arf6 Inner ear Ptprq Vestibular Myo6 Hair cells Actin Elmod1 
GenomicsCell-type identity of the avian utricle
Cell-type identity of the avian utricle
PRJNA877608 | ENA
ProteomicsRat utricle hair bundles and whole utricles—LTQ
Purified utricle hair bundles and utricular epithelium from P3-P7 rat inner ears were analyzed by LC-MS/MS to determine the abundant and enriched proteins of the hair bundle. This dataset used a Thermo LTQ mass spectrometer for protein detection.
ORGANISM(S): Rattus norvegicus (Rat) 
2015-11-17 | PXD002416 | Pride
Vestibular Hair cells Stereocilia Utricle 
ProteomicsMouse utricle hair bundles and whole utricles—Velos
Purified utricle hair bundles and utricular epithelium from P21-P25 mouse inner ears were analyzed by LC-MS/MS to determine the abundant and enriched proteins of the hair bundle. This dataset used a Thermo LTQ Velos mass spectrometer for protein detection.
ORGANISM(S): Mus musculus (Mouse) 
2015-11-17 | PXD002415 | Pride
Vestibular Hair cells Stereocilia Utricle 
TranscriptomicsGene Expression from hair cells and supporting cells in chick utricle
In adult mammals, hair cell loss is irreversible and may result in hearing and balance deficits. In contrast, birds can regenerate hair cells through differentiation of supporting cells and restore inner ear function, suggesting that hair cell progenitors are present in the population of supporting ...
ORGANISM(S): Gallus gallus 
2016-05-17 | E-GEOD-81461 | biostudies-arrayexpress
GenomicsscRNA-seq of P2 and P7 mouse cochlea and utricle
scRNA-seq of P2 and P7 mouse cochlea and utricle
PRJNA722977 | ENA
ProteomicsChick utricle hair bundles and utricular epithelium—Velos
Purified hair bundles and utricular epithelium from E19-E20 chick inner ears were analyzed by LC-MS/MS to determine the abundant and enriched proteins of the hair bundle. This dataset used a Thermo LTQ Velos mass spectrometer for protein detection.
ORGANISM(S): Gallus gallus (Chicken) 
2015-11-17 | PXD002414 | Pride
Vestibular Hair cells Stereocilia Utricle 
ProteomicsReprocessed: Chick utricle hair bundles and utricular epithelium—Orbitrap
This is a reanalysis of PXD000104. Purified hair bundles and utricular epithelium from E19-E20 chick inner ears were analyzed by LC-MS/MS to determine the abundant and enriched proteins of the hair bundle. This dataset used a Thermo Orbitrap Elite mass spectrometer for protein detection.
ORGANISM(S): Gallus gallus (Chicken) 
2015-11-17 | PXD002445 | Pride
Vestibular Hair cells Stereocilia Utricle 
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