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ProteomicsMouse Stereocilia Capping Protein Immunoaffinity Purification
Capping protein controls stereocilia length and width during hair bundle development. To determine what other proteins are involved in capping protein regulation, we carried out immunoaffinity purifications targeted at either CAPZA or CAPZB2. The starting material for immunopurification was crude st...
ORGANISM(S): Mus musculus (Mouse) 
2017-08-25 | PXD006077 | Pride
Auditory Balance Vestibular Hair cells Stereocilia Hearing Actin Twinfilin Capz Hair bundle 
ProteomicsD10 Stereocilia Membrane Enrichment
Through its activity in stereocilia, MYO7A (myosin VIIA) is essential for hair cell function in the inner ear. Utilizing multiple stages of immunoaffinity enrichment, we have developed a strategy that allows us to partially purify stereocilia membranes from thousands of chick inner ears and isolate ...
ORGANISM(S): Gallus gallus (Chicken) 
2016-08-16 | PXD004222 | Pride
Auditory Inner ear Vestibular Stereocilia Chicken Hair cells Hair bundles 
ProteomicsMyosin VIIA 138-1 immunoaffinity purification
Through its activity in stereocilia, MYO7A (myosin VIIA) is essential for hair cell function in the inner ear. Utilizing multiple stages of immunoaffinity enrichment, we have developed a strategy that allows us to partially purify stereocilia membranes from thousands of chick inner ears and isolate ...
ORGANISM(S): Gallus gallus (Chicken) 
2016-08-16 | PXD004221 | Pride
Auditory Myosin Vestibular Stereocilia Hair cell Pdz Hair bundle 
ProteomicsComparison of hair bundle proteomes from WT and Pls1-knockout mouse utricles
With their stereotyped dimensions and orderly arrangement, as well as their essential role in auditory and vestibular function, stereocilia of sensory hair cells provide a particularly prominent example of the importance of cellular actin protrusions. Uniformity of actin packing in stereocilia is me...
ORGANISM(S): Mus musculus (Mouse) 
2016-09-28 | PXD004044 | Pride
Fascin Vestibular Fimbrin Hair cells Stereocilia Espin Plastin Utricle 
UnknownSpontaneous calcium transients in hair cell stereocilia.
Not available
S-EPMC11343103 | biostudies-literature
UnknownSpontaneous calcium transients in hair cell stereocilia.
Not available
S-EPMC12480455 | biostudies-literature
UnknownControl of stereocilia length during development of hair bundles.
Not available
S-EPMC10101650 | biostudies-literature
UnknownGRXCR2 Regulates Taperin Localization Critical for Stereocilia Morphology and Hearing.
Not available
S-EPMC6317715 | biostudies-literature
UnknownSound-induced length changes in outer hair cell stereocilia.
Not available
S-EPMC3594849 | biostudies-literature
UnknownVASCilia (Vision Analysis StereoCilia): A Napari Plugin for Deep Learning-Based 3D Analysis of Cochlear Hair Cell Stereocilia Bundles.
Not available
S-EPMC11212889 | biostudies-literature
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