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This study comprehensively investigates the photoprotective effects of aloin against UVB-induced damage in HaCaT cells, elucidating its antioxidant capacity and its role in preventing cellular apoptosis. The proteomic effect of 50 μg/mL aloin on HaCaT cell damage induced by UVB was evaluated through...
ORGANISM(S): Homo sapiens (Human) 
2025-08-04 | PXD060808 | Pride
C/EBPβ Deficiency Enhances Keratinocyte Apoptosis after UVB-Induced DNA Damage via Regulation of the Type I IFN and TNF Responses
The epidermis is routinely subjected to DNA damage induced by solar (UVB) radiation. In addition to activating canonical DNA damage responses such as cycle cell checkpoints and DNA repair, UVB-induced DNA damage can also activate additional signaling pathways including inflammatory responses. The pa...
ORGANISM(S): Mus musculus 
2026-04-01 | GSE305019 | GEO
BCL11A deficiency protects epidermis from UVB-induced damage through promotion of autophagy
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