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ProteomicsRepo-Man/PP1 regulates heterochromatin formation in interphase
GST:Repo-Man(C-terminus) or GST:alone were expressed as in Vagnarelli et al. 2011. Before elution, beads were first incubated with nucleosomes extracted from HeLa. HeLa cells were lysed and nucleosomes were digested with MNase (20min, 37C). Nucleosomes were firstly incubated with GST alone for 2hrs....
ORGANISM(S): Homo sapiens (Human) 
2016-12-07 | PXD004613 | Pride
Human Shotgun proteomics heretochromatin Hela Repo-man 
ProteomicsKi-67 is necessary during DNA replication for forks protection and genome stability
Ki-67 molecular functions and properties have remained quite obscure for a long time, despite its importance as a major proliferation marker in clinic. Only recently it has been shown that Ki-67 has a major role in the formation of the mitotic chromosome periphery compartment, and it is a protein ph...
ORGANISM(S): Homo sapiens (Human) 
2024-04-13 | PXD037513 | Pride
Ki-67 Silac Genome stability Cell cycle Dna replication 
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