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Analysis of the genomic expression profiles in Interspecific recombinant Congenic Strains starting from a Mus msuculus x mus spretus cross.
ORGANISM(S): Mus musculus x Mus spretus 
STOX1 overexpressing placentas generate preeclampsia-like symptoms in pregnant mice. These symptoms are reverted by aspirin. The experiment aims at analyzing placental expression in Transgenic/non transgenic with and withou aspirin, in the placentas at 16,5 days post-coïtum. There are two strains of...
ORGANISM(S): Mus musculus 
Neonates born pre-term or/and at low weight often suffer from defective lung function where PPAR-gamma cascades play an important role. Curcumin is a PPAR gamma agonist
ORGANISM(S): Rattus norvegicus 
Pregnant rats were randomly divided into two groups. Dams were then housed individually and fed throughout gestation a 22 % protein diet, representing the control group (C, n=5), or an 9% isocaloric protein diet, representing the low-protein (LP, n=6). Both diets were isocaloric, because the protei...
ORGANISM(S): Rattus norvegicus 
All genome expression changes investigated on pools of growth restricted rats (at term) compared to control rats. The protocol of growth restriction (length, duration) has been extensively described in Buffat et al (Journal of Pathology 2007a and Endocrinology, 2007b) Ten hybridizations, two technic...
ORGANISM(S): Rattus norvegicus 
The epigenetic effects of STOX1A was evaluated through demethylation treatment by AZA-cytidine on control or STOX1A overexpressing JEG3 cells
ORGANISM(S): Homo sapiens 
Endometriosis is a common gynecological disorder characterized by pain and infertility, where the lesions disseminate everywhere in the body with a preference for the pelvis. In that, it could be regarded as a “benign metastatic disease”, since its issue is not fatal. However, the molecular base...
ORGANISM(S): Homo sapiens 
Trophoblast fusion is a central step in placental physiology. This mechanisms can be studied in the BeWO cell model that fuse following forskolin treatment that activates the c-AMP cascade.
ORGANISM(S): Homo sapiens 
This experiment is one of a series of experiments on interspecific recombinant congenic strain (IRCS) mice that aimed to identify novel genes involved in male or female hyporfertility by comparing characteristics of the sperm, number of offspring, quality of implantation etc. in C57B6/J and IRCS mi...
ORGANISM(S): Mus musculus 
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