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UnknownContext-Dependent Requirement of Euchromatic Histone Methyltransferase Activity during Reprogramming to Pluripotency.
Not available
S-EPMC7724475 | biostudies-literature
TranscriptomicsExpression data from HeLa cells treated with Casiopeina Cas-II-gly
Copper-based chemotherapeutic compounds Casiopeinas, have been presented as able to promote selective programmed cell death in cancer cells, thus being proper candidates for targeted cancer therapy. DNA fragmentation and apoptosis -in a process mediated by reactive oxygen species- for a number of tu...
ORGANISM(S): Homo sapiens 
2012-10-31 | E-GEOD-41827 | biostudies-arrayexpress
TranscriptomicsAltering the intestinal microbiota during a critical developmental window has lasting metabolic consequences [8_week_ileal]
Acquisition of the intestinal microbiota begins at birth, and a stable microbial community develops from a succession of key organisms. Disruption of the microbiota during maturation by low-dose antibiotic exposure can alter host metabolism and adiposity. We now show that low-dose penicillin (LDP), ...
ORGANISM(S): Mus musculus 
2014-09-01 | E-GEOD-58085 | biostudies-arrayexpress
TranscriptomicsAltering the intestinal microbiota during a critical developmental window has lasting metabolic consequences [30_week_Liver]
Acquisition of the intestinal microbiota begins at birth, and a stable microbial community develops from a succession of key organisms. Disruption of the microbiota during maturation by low-dose antibiotic exposure can alter host metabolism and adiposity. We now show that low-dose penicillin (LDP), ...
ORGANISM(S): Mus musculus 
2014-09-01 | E-GEOD-58086 | biostudies-arrayexpress
TranscriptomicsAnalysis of Gene expression of human Th17 and Th1 clones
Human T cell clones were derived according to standard protocols using different mix of cytokines, once assessed for their functional profile were studied for gene expression. The purpose of this study is to analyze human Th1 and Th17 clones with and without stimulation with PMA and Ionomycin to mea...
ORGANISM(S): Homo sapiens 
2012-02-27 | E-GEOD-30664 | biostudies-arrayexpress
TranscriptomicsMicroarray hybridization data from the root tips of 5-day-old Arabidopsis thaliana seedlings grown on tilted, hard agar surfaces
The growth behavior of plant roots on tilted, hard agar surfaces is determined by many basic cellular processes, including microtubule dynamics and cell wall expansion. Among Arabidopsis thaliana accessions there is natural variation for these behaviors, including one known as skewing or slanting. ...
ORGANISM(S): Arabidopsis thaliana 
2011-03-31 | E-GEOD-28275 | biostudies-arrayexpress
TranscriptomicsmiR-1204 promotes tumor development in breast and ovarian cancer cell lines
Introduction: Amplification at chromosome 8q24 is one of the most frequent genomic abnormalities in human cancers and is associated with reduced survival duration in breast and ovarian cancers. The minimal amplified region encodes c-MYC and the non-coding RNA, PVT1 including miR-1204 encoded in exon...
ORGANISM(S): Homo sapiens 
2012-04-30 | E-GEOD-37185 | biostudies-arrayexpress
TranscriptomicsEffect of glucose, endothelin-1 and cortisol on human iPS-derived cardiomyocytes
Analysis of human iPS-derived cardiomyocytes exposed to glucose, endothelin-1 and cortisol in vitro. Treatment produces a surrogate diabetic cardiomyopathic phenotype. Results provide insight into the pathways regulated by the treatment in the cardiomyocyte. The RNA for each vehicle-control treated ...
ORGANISM(S): Homo sapiens 
2014-10-10 | E-GEOD-62203 | biostudies-arrayexpress
TranscriptomicsIntegrated Genomic Analysis of Relapsed Childhood Acute Lymphoblastic Leukemia reveals therapeutic strategies
This SuperSeries is composed of the following subset Series: GSE28460: Expression data from ALL diagnosis and relapse pediatric acute lymphoblastic leukemia cases GSE28461: Promoter methylation data from ALL diagnosis and relapse pediatric acute lymphoblastic leukemia cases Refer to individual Serie...
ORGANISM(S): Homo sapiens 
2011-09-22 | E-GEOD-28462 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of various cell types isolated from pancreatic islet grafts in Id1/Id3 deficient and wild type mice
To gain insights into the genetic program activated within the distinct vascular and inflammatory transplant microenvironments in Id1/Id3 deficient and WT mice, we performed a series of gene screening experiments using RNA from total graft tissue as well as from myeloid and endothelial (i.e., CD31+ ...
ORGANISM(S): Mus musculus 
2008-06-13 | E-TABM-355 | biostudies-arrayexpress
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