Sort   by:  
 Page size 
TranscriptomicsThe RNA-binding protein RBM47 suppresses metastatic breast cancer progression
Through integrative analysis of clinical breast cancer gene expression datasets, cell line models of breast cancer progression, and mutation data from cancer genome resequencing studies, we have identified RNA binding motif protein 47 (RBM47) as a candidate suppressor of breast cancer metastasis. RB...
ORGANISM(S): Homo sapiens 
2014-06-11 | E-GEOD-53779 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human uterine fibroids with mutated or wild type fumarate hydratase gene
A series of gene expression measurements of uterine fibroids with mutated or wild-type fumarate hydratase (FH) gene.
ORGANISM(S): Homo sapiens 
2007-08-25 | E-GEOD-2152 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human fibriods vs. normal myometrium with mutated or wild type fumarate hydratase (FH) gene reveals distinct expression profiles in fumarate-hydratase-deficient uterine fibroids.
A series of gene expression measurements of normal myometrium and uterine fibroids with mutated or wild-type fumarate hydratase (FH) gene.
ORGANISM(S): Homo sapiens 
2007-10-02 | E-GEOD-2725 | biostudies-arrayexpress
UnknownHSP70 induces liver X receptor pathway activation and cholesterol reduction in vitro and in vivo.
Not available
S-EPMC6822257 | biostudies-literature
TranscriptomicsTranscription profiling of human uterine fibroids and normal myometrium
Defects in mitochondrial enzymes predispose to severe developmental defects as well as tumorigenesis. Heterozygous germline mutations in the nuclear gene encoding fumarate hydratase (FH), an enzyme catalyzing the hydration of fumarate in the Krebs tricarboxylic acid cycle, cause hereditary leiomyoma...
ORGANISM(S): Homo sapiens 
2007-10-02 | E-GEOD-2724 | biostudies-arrayexpress
ProteomicsLineage factor-dependent signalling by kidney cancer-associated genetic alteration
As shown by large-scale human genetic data, cancer mutations display strong tissue-selectivity, but how this selectivity arises remains unclear. Here, using experimental models, functional genomics and analysis of patient samples, we demonstrate that the lineage transcription factor paired box 8 ...
ORGANISM(S): Homo sapiens (Human) 
2022-03-14 | PXD029522 | Pride
Renal cell carcinoma Lineage factors Pax8 Hif2a 
TranscriptomicsTranscription profiling of human colorectal serrated adenocarcinomas and conventional adenocarcinomas reveals they are a molecular subclass as well as morphologically distinct
Serrated adenocarcinomas are morphologically different from conventional adenocarcinomas. The serrated pathway has recently been proposed to represent a novel mechanism of colorectal cancer (CRC) formation. However, whether they are biologically different and truly form a distinct subclass of CRC, i...
ORGANISM(S): Homo sapiens 
2007-10-27 | E-GEOD-4045 | biostudies-arrayexpress
UnknownHomophilic CD44 Interactions Mediate Tumor Cell Aggregation and Polyclonal Metastasis in Patient-Derived Breast Cancer Models.
Not available
S-EPMC6328322 | biostudies-literature
UnknownEndogenous HIF2A reporter systems for high-throughput functional screening.
Not available
S-EPMC6089976 | biostudies-literature
TranscriptomicsFlag-RBM47 HITS-CLIP in brain metastatic derivatives of MDA-MB-231
Brain metastatic breast cancer cells were subjected to HITS-CLIP to identify the targets of the RNA binding protein RBM47 MDA231-BrM2a is characterized in PMID: 19421193; Related data published together with these data are found in GSE53779 Non-clonal brain metastatic breast cancer cells stably exp...
ORGANISM(S): Homo sapiens 
2014-06-11 | E-GEOD-58380 | biostudies-arrayexpress
Sort   by:  
 Page size