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ProteomicsVap33 protein interactome - The Drosophila tumor suppressors Lgl and Vap33 activate the Hippo pathway by a dual mechanism involving RtGEF/Git/Arf79F and inhibition of the V-ATPase
To identify Vap33 binding proteins, we purified Vap33-containing protein complexes from Drosophila embryos, using the single-step GFP-trap bead purification from a fly line expressing YFP-tagged Vap33, followed by nanoLC-MS/MS analysis of the interactors. This study revealed the binding of Vap33 to ...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2024-02-01 | PXD035110 | Pride
Vap33 Embryo Drosophila 
UnknownThe Drosophila tumour suppressor Lgl and Vap33 activate the Hippo pathway through a dual mechanism.
Not available
S-EPMC10911279 | biostudies-literature
UnknownLgl reduces endosomal vesicle acidification and Notch signaling by promoting the interaction between Vap33 and the V-ATPase complex.
Not available
S-EPMC6437781 | biostudies-literature
UnknownThe Vap33 signaling axis precisely coordinates the timing of motoneuron dendritogenesis in neural map development.
Not available
S-EPMC12678556 | biostudies-literature
ProteomicsLgl protein interactome - Lgl reduces endosomal vesicle acidification and Notch signaling by promoting the interaction between Vap33 and the V-ATPase complex
To identify Lgl binding proteins, we purified Lgl-containing protein complexes from cultured Drosophila S2 cells, using the single-step streptavidin purification from stable cell lines expressing SBP-tagged Lgl, followed by nanoLC-MS/MS analysis of the interactors. This study revealed the binding of...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2018-06-10 | PXD009568 | Pride
Lgl S2 cells Drosophila 
ProteomicsVAP-mediated membrane tethering mechanisms implicate ER-PM contact function in pH homeostasis
MS analyses of interactome of full-length (i.e., Scs2 and Scs22) and TM-truncated (i.e., Scs2N and Scs22N) fission yeast VAPs.
ORGANISM(S): Schizosaccharomyces Pombe (fission Yeast) 
2024-08-09 | PXD053887 | JPOST Repository
UnknownMouse VAP33 is associated with the endoplasmic reticulum and microtubules.
Not available
S-EPMC15535 | biostudies-literature
UnknownMiga-mediated endoplasmic reticulum-mitochondria contact sites regulate neuronal homeostasis.
Not available
S-EPMC7556861 | biostudies-literature
UnknownSecretion of endoplasmic reticulum protein VAPB/ALS8 requires topological inversion.
Not available
S-EPMC11467184 | biostudies-literature
TranscriptomicsVAPB regulates proliferation in medulloblastoma
RNA sequencing of medulloblastoma cell lines DAOY and USP13-med; wild type and VAPB KO.
ORGANISM(S): Homo sapiens 
2023-06-28 | E-MTAB-11914 | biostudies-arrayexpress
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