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TranscriptomicsRNA clamping by Vasa assembles a piRNA Amplifier complex on transposon transcripts
Germline-specific Piwi-interacting RNAs (piRNAs) protect the genome against selfish genetic elements and are essential for fertility in animals. piRNAs targeting active transposons are amplified by a feed-forward loop known as the Ping-pong cycle, which links endonucleolytic slicing of target RNA...
ORGANISM(S): Bombyx mori 
2014-06-04 | E-GEOD-57420 | biostudies-arrayexpress
GenomicsCoracopsis vasa
Coracopsis vasa
PRJNA479489 | ENA
GenomicsCoracopsis vasa
Coracopsis vasa overview
PRJNA480060 | ENA
ProteomicsGermline maintenance through the multifaceted activities of GLH/Vasa in Caenorhabditis elegans P granules
Vasa is a highly conserved member of the ATP-dependent DEAD box helicase family, a multipotency factor, and a critical component for the specification and maintenance of the germline. Its homologs have been shown to regulate translation, small RNA amplification, and serve as a molecular solvent for ...
ORGANISM(S): Caenorhabditis elegans 
2019-06-07 | PXD014135 | Pride
Vasa C. elegans Glh-1 Glh-1 coip 
TranscriptomicsSingle-cell total RNA sequencing (VASA-seq) on index-sorted human colonic chip infected by wild-type S.Tm
We infected adult human intestine epithelium stem cell derived colonic chip with wild-type S.Tm 14028 with GFP label. To link intracellular replication levels to host response, we performed single-cell total RNA sequencing (VASA-seq) on index-sorted cells from GFPLow, GFPInt and GFPHigh levels.
ORGANISM(S): Homo sapiens 
2026-08-17 | E-MTAB-17486 | biostudies-arrayexpress
UnknownCore outcome set for studies on pregnant women with vasa previa (COVasP): a study protocol.
Not available
S-EPMC7371138 | biostudies-literature
UnknownInpatient vs outpatient management of pregnancies with vasa previa: A historical cohort study.
Not available
S-EPMC10577631 | biostudies-literature
GenomicsK562+mESC VASA-seq
Single cell sequencing with VASA-seq of K562 and mESC cells
PRJEB67547 | ENA
TranscriptomicsUAP56 couples piRNA clusters to the perinuclear transposon silencing machinery [tiling array]
The transposon silencing piRNAs are produced from precursors that are encoded by heterochromatic clusters and processed in the perinuclear nuage. We show that the Drosophila nuclear DEAD box protein UAP56, previously implicated in mRNA splicing and nuclear export, co-localizes with the cluster-assoc...
ORGANISM(S): Drosophila melanogaster 
2012-11-28 | E-GEOD-35636 | biostudies-arrayexpress
ProteomicsGLH/VASA helicases promote germ granule formation to ensure the fidelity of piRNA-mediated transcriptome surveillance
The ability to distinguish non-self from self is the key characteristic for any defense system. piRNAs function as guardians of the genome by silencing non-self nucleic acids and transposable elements in animals. Many piRNA factors are enriched in perinuclear germ granules, but whether their localiz...
ORGANISM(S): Caenorhabditis elegans 
2022-08-05 | PXD033506 | Pride
Glh-1 Vasa 
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