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TranscriptomicsTranscription profiling of adherent and non-adherent human hematopoietic progenitor cells
Comparison of gene expression of the adherent and non-adherent fraction of hematopoietic progenitor cells.
ORGANISM(S): Homo sapiens 
2007-03-13 | E-MEXP-586 | biostudies-arrayexpress
TranscriptomicsscRNA-seq of Mus musculus subcutaneous Lin- cells derived from the subcutaneous adipose stromal vascular fraction
We used the resolving power of single-cell transcriptional profiling to molecularly characterize the mouse adipose stem and progenitor cell-enriched, subcutaneous adipose stromal vascular fraction. We molecularly assessed CD45- CD31- SVF cells using the 10x Genomics Chromium (10x) platform.
ORGANISM(S): Mus musculus 
2019-05-24 | E-MTAB-6677 | biostudies-arrayexpress
TranscriptomicsReprogramming of Endothelium Into Hematopoietic Progenitors by Defined Factors and Vascular Induction
Generation of abundant engraftable hematopoietic cells from autologous tissues promises new therapies for hematologic diseases. Differentiation of pluripotent stem cells into hematopoietic cells results in emergence of cells that have poor engraftment potential. To circumvent this hurdle, we have d...
ORGANISM(S): Homo sapiens 
2014-07-11 | E-GEOD-57662 | biostudies-arrayexpress
ProteomicsProteomics characterization of VPCs
hESCs were differentiated into vascular progenitor cells, using defined growth conditions. Initial population of SCs and the two derivative CD34 positive and CD34 negative populations were analyzed using mass spectrometry.
ORGANISM(S): Homo sapiens (Human) 
2016-09-28 | PXD003606 | Pride
Angiogenesis Vascular progenitor cells Cd34 
MetabolomicsHuman umbilical cord-derived mesenchymal stem cells ameliorate perioperative neurocognitive disorder by inhibiting inflammatory responses and activating BDNF/TrkB/CREB signaling pathway in aged mice

BACKGROUND: Perioperative neurocognitive disorder (PND) is a key complication affecting older individuals after anesthesia and surgery. Failure to translate multiple pharmacological therapies for PND from preclinical studies to clinical settings has necessitated the exploration o...

2023-07-25 | MTBLS7759 | MetaboLights
ProteomicsTHE ATHEROMA PLAQUE SECRETOME STIMULATES THE MOBILIZATION OF ENDOTHELIAL PROGENITOR CELLS EX VIVO
in this study we evaluated the initial response promoted by the atherosclerotic plaque (AP) secreted factors over healthy endothelial progenitor cells (EPCs), in order to understand the mechanisms underlying the neovascularization and vascular remodeling properties assigned to these cells and to use...
ORGANISM(S): Homo sapiens (Human) 
2018-10-02 | PXD005465 | Pride
Lc-msms Endothelial progenitor cells Secretome 
TranscriptomicsAdenosine-treated endothelial progenitor cells
The goal of this study was to investigate the effects of the cardioprotective nucleoside adenosine on gene expression in early and late endothelial progenitor cells. Adenosine mod Early outgrowth endothelial progenitor cells were obtained by adhesion of peripheral blood mononuclear cells of healthy ...
ORGANISM(S): Homo sapiens 
2011-01-29 | E-GEOD-26744 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human samples after exercise training to characterize a colony assay used to investigate endothelial progenitor cells
Subjects underwent endothelial testing and blood sampling at baseline and after 3 months of exercise training. Microarray and flow cytometry-based characterization of cells from an endothelial progeniator colony assay was consistent with T lymphocytes, but not endothelial cells. Experiment Overall ...
ORGANISM(S): Homo sapiens 
2009-01-13 | E-GEOD-12155 | biostudies-arrayexpress
TranscriptomicsGenetic module and miRNome trait analyses reflect the distinct biological features of endothelial progenitor cells from different anatomic locations
Background: Endothelial progenitor cells (EPCs) play a fundamental role in post-natal vascular repair, yet EPCs from different anatomic locations possess unique biological properties. The underlying mechanisms are unclear. Method: We performed transcriptome analysis for EPCs isolated from 2 diff...
ORGANISM(S): Homo sapiens 
2012-09-21 | E-GEOD-39763 | biostudies-arrayexpress
TranscriptomicsMicroarray of neural progenitor cells from neonatal lung injury mice treated with placebo or umbilical-cord mesenchymal stromal cell extracellular vesicles or untreated, as well as age-matched control mice
The purpose of this experiment was to determine the transcriptional differences between neural progenitor cells from neonatal lung injury mice vs. control mice, as well as neonatal lung injury mice treated with umbilical-cord mesenchymal stromal cell extracellular vesicles vs. neonatal lung injury m...
ORGANISM(S): Mus musculus 
2022-05-17 | E-MTAB-11157 | biostudies-arrayexpress
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