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TranscriptomicsEnvironment-responsive transcription factors bind proto-silencer elements and regulate subtelomeric silencing
Subtelomeric chromatin is subject to evolutionarily conserved complex epigenetic regulation and is implicated in numerous aspects of cellular function including formation of heterochromatin, regulation of different stress response pathways, and control of lifespan. Subtelomeric DNA is characterized...
ORGANISM(S): Saccharomyces cerevisiae 
2011-05-02 | E-GEOD-21852 | biostudies-arrayexpress
UnknownDevelopment of mirror-image monobodies targeting the oncogenic BCR::ABL1 kinase.
Not available
S-EPMC11666773 | biostudies-literature
TranscriptomicsTranscriptional profiling of yeast transcription factor deletion strains (rox1, xbp1 or phd1) and wild-type strains in response to hydrogen peroxide or butanol
The goal of this study was to determine the effect of transcription factor deletions on the expression of subtelomeric genes in the presence of environmental stimuli. This study is a component of a larger study, which identified that environment-responsive transcription factors bind proto-silencer e...
ORGANISM(S): Saccharomyces cerevisiae 
2011-05-16 | E-GEOD-21926 | biostudies-arrayexpress
TranscriptomicsExpression data from HeLa cells treated with Casiopeina Cas-II-gly
Copper-based chemotherapeutic compounds Casiopeinas, have been presented as able to promote selective programmed cell death in cancer cells, thus being proper candidates for targeted cancer therapy. DNA fragmentation and apoptosis -in a process mediated by reactive oxygen species- for a number of tu...
ORGANISM(S): Homo sapiens 
2012-10-31 | E-GEOD-41827 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human biopsies from subcutaneous adipose tissue from unrelated individuals reveals galanin preproprotein is associated with elevated plasma triglycerides
Assessment of mRNA expression levels in fat biopsies from subcutaneous adipose tissue from unrelated individuals. Experiment Overall Design: Subcutaneous adipose tissue from 49 unrelated individuals.
ORGANISM(S): Homo sapiens 
2009-01-17 | E-GEOD-13506 | biostudies-arrayexpress
UnknownZooming in the plastisphere: the ecological interface for phytoplankton-plastic interactions in aquatic ecosystems.
Not available
S-EPMC11885710 | biostudies-literature
TranscriptomicsGenome-wide identification of binding sites of Evi1 in human myeloid cell lines
The EVI1 gene codes for a transcription factor with important roles in development and leukemogenesis. Overexpression of EVI1 in acute myeloid leukemia (AML) is one of the worst prognostic factors in patients with and without 3q26 rearrangements. Evi1 acts in several pathways through the interaction...
ORGANISM(S): Homo sapiens 
2012-09-30 | E-GEOD-16238 | biostudies-arrayexpress
UnknownSenescent endothelial cells promote pathogenic neutrophil trafficking in inflamed tissues
Not available
S-SCDT-10_1038-S44319-024-00182-X | biostudies-other
UnknownEffect of Direct Transportation to Thrombectomy-Capable Center vs Local Stroke Center on Neurological Outcomes in Patients With Suspected Large-Vessel Occlusion Stroke in Nonurban Areas: The RACECAT Randomized Clinical Trial.
Not available
S-EPMC9073661 | biostudies-literature
UnknownElevating fungal care: bridging Brazil's healthcare practices to global standards.
Not available
S-EPMC11960063 | biostudies-literature
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