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ProteomicsVDAC2 promotes BAX apoptotic activity
Intrinsic apoptosis is critical for normal physiology including the prevention of tumor formation. BAX and BAK, which are essential for mediating this process and for the cytotoxic action of many anti-cancer drugs, are thought to be regulated through similar mechanisms and act redundantly to drive a...
ORGANISM(S): Mus musculus (Mouse) 
2018-10-29 | PXD011195 | Pride
Cancer Bak Bax Mitochondria Voltage-dependent anion channel. Bcl-2 Apoptosis 
ProteomicsSuccination of Tubulin and VDAC2 in the Mouse Brainstem
Elevated fumarate concentrations resulting from inhibition of the Krebs cycle lead to increases in protein succination, an irreversible post-translational modification that occurs when fumarate reacts with cysteine residues to generate S-(2-succino)cysteine (2SC). Metabolic events that reduce NADH r...
ORGANISM(S): Mus musculus (Mouse) 
2015-10-16 | PXD002991 | Pride
Succination tubulin vdac2 
GenomicsTargeting Vdac2 enables IFNg-mediated destruction and inflammatory remodeling of tumors to overcome immune evasion [microarray 6]
Targeting Vdac2 enables IFNg-mediated destruction and inflammatory remodeling of tumors to overcome immune evasion [microarray 6]
PRJNA1176714 | ENA
GenomicsSTING governs RCC growth through mitochondrial regulation of VDAC2
STING governs RCC growth through mitochondrial regulation of VDAC2
PRJNA788511 | ENA
UnknownMYBL2 guides autophagy suppressor VDAC2 in the developing ovary to inhibit autophagy through a complex of VDAC2-BECN1-BCL2L1 in mammals.
Not available
S-EPMC4590641 | biostudies-literature
GenomicsTargeting Vdac2 overcomes immunotherapy resistance by inducing tumor cell death and inflammation [microarray 4]
Targeting Vdac2 overcomes immunotherapy resistance by inducing tumor cell death and inflammation [microarray 4]
PRJNA1087424 | ENA
UnknownVDAC2-specific cellular functions and the underlying structure.
Not available
S-EPMC5092071 | biostudies-literature
TranscriptomicsTargeting Vdac2 enables IFNg-mediated destruction and inflammatory remodeling of tumors to overcome immune evasion [microarray 6]
Microarray analysis of WT, Vdac2 KO, Bim/Bid dKO and Vdac2/Bim/Bid TKO B16-OVA tumor cells after IFNg treatment for 24 hours.
ORGANISM(S): Mus musculus 
2025-03-19 | GSE280185 | GEO
GenomicsTargeting VDAC2 enables IFNg-mediated destruction and inflammatory remodeling of tumors to overcome immune evasion [microarray 5]
Targeting VDAC2 enables IFNg-mediated destruction and inflammatory remodeling of tumors to overcome immune evasion [microarray 5]
PRJNA1176705 | ENA
UnknownVDAC2 and the BCL-2 family of proteins.
Not available
S-EPMC8786305 | biostudies-literature
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