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TranscriptomicsAge Dependent Gene Expression Responses to Inhaled Lipopolysaccharide Combined with Mechanical Ventilation
Children have a lower incidence and mortality from acute lung injury than adults, and infections are the most common event associated with acute lung injury (ALI). To study the effects of age on susceptibility to ALI, we investigated the responses to microbial products combined with mechanical vent...
ORGANISM(S): Mus musculus 
2009-11-23 | E-GEOD-18341 | biostudies-arrayexpress
TranscriptomicsOpen lung approach with low tidal volume mechanical ventilation attenuates lung injury in rats with massive brain damage
Introduction: The ideal ventilation strategy for patients with massive brain damage requires better elucidation. We hypothesized that in the presence of massive brain injury, a ventilation strategy using low (6 mL/kg) tidal volume (VT) ventilation with open lung positive end-expiratory pressure set ...
ORGANISM(S): Rattus norvegicus 
2014-04-24 | E-GEOD-52142 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of lung samples from mouse and rat treated with mechanical ventilation
This series contain mouse and rat lung samples treated with mechanical ventilation and corresponded controls.
ORGANISM(S): Mus musculus 
2007-07-20 | E-GEOD-2368 | biostudies-arrayexpress
ProteomicsEffect of lung ventilation and acid treatment on mouse lung proteome
Lung tissue samples were collected from mice allowed to breath freely (FB) or on ventilation (LV) devices, either saline or acid treatment (four sample groups FB_saline; FB_acid; LV_saline; LV_acid)
ORGANISM(S): Mus musculus (Mouse) 
2020-09-10 | PXD013485 | Pride
Shotgun proteomics Ventilation Lung function 
GenomicsHigh Frequency Ventilation in Premature Infants (HIFI-BioLINCC)
High Frequency Ventilation in Premature Infants (HIFI-BioLINCC)
PRJNA1254792 | ENA
GenomicsHigh Frequency Ventilation in Premature Infants (HIFI-BioLINCC)
High Frequency Ventilation in Premature Infants (HIFI-BioLINCC)
PRJNA1254793 | ENA
TranscriptomicsTranscription profiling of murine lungs to investigate the role of mechanical ventilation in modulating lungs transcriptional response to lipopolysaccharide (LPS)
This experiment investigated the role of mechanical ventilation (MV) in modulating lung's transcriptional response to LPS. Twenty four C57/B6 male mice were randomized to four groups: 1. Control, 2. MV, 3. LPS and 4. MV+LPS. Expression profiling of whole lungs revealed a significant augmentation...
ORGANISM(S): Mus musculus 
2007-08-31 | E-GEOD-2411 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat mechanically ventilated lungs from strains resistant or susceptible to ventilation-associated lung injury (VALI)
We sought to confirm the genetic influence in the development of Ventilation-Associated Lung Injury (VALI) and, in the process, identify potential candidate genes involved in the disease by integrating differential gene expression profiling on rat lungs to a traditional strain survey analysis of the...
ORGANISM(S): Rattus norvegicus 
2007-10-31 | E-GEOD-7041 | biostudies-arrayexpress
UnknownHealth-related quality of life as predictor for mortality in patients treated with long-term mechanical ventilation.
Not available
S-EPMC6330471 | biostudies-literature
TranscriptomicsMAP Kinase Phosphatase-1 Modulates Regional Effects of Injurious Mechanical Ventilation in Rodent Lungs
Scientific knowledge on the subjects: Injurious mechanical ventilation amplifies acute lung injury in a heterogeneous and regional fashion but the molecular mechanisms underlying regional lung injury and the protective effects of prone positioning are unclear. Regionally injurious ventilation is ass...
ORGANISM(S): Rattus norvegicus 
2011-08-26 | E-GEOD-31678 | biostudies-arrayexpress
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