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TranscriptomicsAnalysis of the Aloe vera transcriptome using the Affymetrix ATH1 GenChip
The Aloe vera transcriptome was analysed by hybridising triplicate samples of root and leaf tissue to the Affymetrix Arabidopsis ATH1 array. In total, 7 samples were hybridised to the array. Samples consisted of 1 genomic DNA, and triplicate samples of leaf and root RNA.
ORGANISM(S): Aloe vera 
2011-03-26 | E-GEOD-24389 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of normal and JAK2V617F-positive erythroblasts of polycythemia vera and essential thrombocythemia
This experiment was designed to identify genes differentially expressed in association with the JAK2V617F mutation in polycythemia vera (PV) and essential thrombocythemia (ET). Peripheral blood was obtained from 20 ET and 16 PV patients and erythroid progenitors were grown in semi-solid methylcellul...
ORGANISM(S): Homo sapiens 
2011-11-22 | E-MTAB-384 | biostudies-arrayexpress
TranscriptomicsGene Expression Profiling in Polycythemia Vera (PV)
To define the molecular abnormalities at the stem cell level in polycythemia vera (PV), we examined global gene expression in circulating CD34+ cells from 19 JAK2 V617F-positive PV patients and 6 normal individuals using Affymetrix oligonucleotide microarray technology. We observed that CD34+ cell g...
ORGANISM(S): Homo sapiens 
2014-08-29 | E-GEOD-47018 | biostudies-arrayexpress
TranscriptomicsMouse miR-210 activity in B-cells
mRNA profiling of miR-210 transgenic (in vivo), mimic-transfected (in vitro) and miR-210 knockout activated mouse B-cells was performed to assess the effect of miR-210 overexpression on the B-cell transcriptome.
ORGANISM(S): Mus musculus 
2013-08-23 | E-MTAB-1758 | biostudies-arrayexpress
TranscriptomicsChanges of miRNA expression in granulocytes of patients with polycythemia vera (PV) and essential thrombocythemia (ET) receiving INCB018424 in a Phase 2 study
A global microRNA expression profile was obtained from gradient-purified granulocytes (>95% pure) collected at the time of screening and at cycle 4 of treatment Protocol #18424-256 is a Phase 2 study of the JAK1 and JAK2 inhibitor INCB01842 in patients with advanced polycythemia vera (PV) and essent...
ORGANISM(S): Homo sapiens 
2012-09-26 | E-GEOD-32194 | biostudies-arrayexpress
ProteomicsInvestigating the proteome of red blood cells and reticulocytes in Polycythemia Vera and Essential Thrombocythemia
The project aims at comparing the effect of the JAK2V617F mutation on protein expression in human erythroid cells in the context of Polycythemia Vera and Essential Thrombocythemia
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD029965 | Pride
Reticulocytes Human red blood cells Erythrocytes Polycythemia vera Nlc-ms/ms Orbitrap fusion Essential thrombocythemia Jak2v617f 
TranscriptomicsTranscription profiling of Kawasaki disease patients who may benefit from methylprednisolone
Clinical score and transcript abundance patterns identify Kawasaki disease patients who may benefit from addition of methylprednisolone. Intravenous immunoglobulin (IVIG) treatment-resistant patients are high risk of developing coronary artery lesions (CALs) with Kawasaki disease (KD). The IVIG-resp...
ORGANISM(S): Homo sapiens 
2010-07-08 | E-GEOD-16797 | biostudies-arrayexpress
TranscriptomicsAberrant DNA methylation profiling of classic Philadelphia Negative Myeloproliferative Neoplasms
Since most DNA methylation studies in Classic Philadelphia-negative myeloproliferative neoplasms (MPNs) M-bM-^@M-^S polycythaemia vera (PV), essential thrombocythaemia (ET), and primary myelofibrosis (PMF) - have been performed on a gene-by-gene basis, a more comprehensive methylation profiling is n...
ORGANISM(S): Homo sapiens 
2013-11-29 | E-GEOD-42042 | biostudies-arrayexpress
TranscriptomicsT. Brucei, Nup-1 Depletion
Organization of the genome into compacted chromatin is a eukaryotic innovation facilitating increased sophistication in transcriptional regulation. In metazoa coiled-coil lamin proteins are major components of the chromatin organizer at the nuclear periphery and maintain nuclear integrity. While ide...
ORGANISM(S): Trypanosoma brucei 
2011-12-15 | E-GEOD-26256 | biostudies-arrayexpress
UnknownCommon clonal origin of three distinct hematopoietic neoplasms in a single patient: B-cell lymphoma, T-cell lymphoma, and polycythemia vera.
Not available
S-EPMC10815289 | biostudies-literature
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