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ProteomicsInherited mitochondrial dysfunction impacts corneal innervation fibre identity, fonctionnality and regenerative potential
The cornea is the transparent tissue covering the anterior part of the eye. Its main roles are to convey the light toward the retina, and to act as a protective barrier against infection or injury for the eye. The transparency of the cornea is a crucial component of its functionality and is the resu...
ORGANISM(S): Mus musculus (Mouse) 
2024-07-25 | PXD052337 | Pride
Epithelium Mitochondria Transcriptomic Opa1 Innervation Proteomic Cornea Tear film 
ProteomicsUnbiased mapping of human cerebrospinal fluid proteome dynamics
Our purpose is to explore the dynamics of a clinically relevant proteome by determining protein turnover, synthesis and breakdown. ]. The alteration of protein turnover represents a new type of biological information which might provide unique insight in disease pathophysiology, e.g. Alzheimer disea...
ORGANISM(S): Homo sapiens (Human) 
2020-01-22 | PXD012462 | Pride
Dynamics Human Csf Protein 
ProteomicsUnbiased mapping of human cerebrospinal fluid proteome dynamics - Profile data
Our purpose is to explore the dynamics of a clinically relevant proteome by determining protein turnover, synthesis and breakdown. ]. The alteration of protein turnover represents a new type of biological information which might provide unique insight in disease pathophysiology, e.g. Alzheimer disea...
ORGANISM(S): Homo sapiens (Human) 
2020-01-22 | PXD012502 | Pride
Ms1 profile data 
ProteomicsDeciphering Black Extrinsic Tooth Stains composition in Children using metaproteomics
The present study focuses on the use of a metaproteomic approach to analyse Black Extrinsic Tooth Stains, a specific type of pigmented extrinsic substance, in a cohort of 96 Children. Metaproteomics is a powerful emerging technology that successfully enabled human protein and bacterial identificatio...
ORGANISM(S): Homo sapiens (Human) 
2024-07-25 | PXD029245 | Pride
Saliva Dental plaque Oral pathology Metaproteomics 
ProteomicsStable Isotope Labeling by Amino acid in Vivo (SILAV)
Intravenous administration of stable isotope labeled amino acid ((13)C6-leucine) to humans recently made it possible to study the metabolism of specific biomarkers in plasma using High Resolution mass spectrometry (MS). This labeling approach could be of great interest for monitoring many leucine-co...
ORGANISM(S): Homo Sapiens 
2025-11-10 | PXD046373 | panorama
ProteomicsModeling the simultaneous dynamics of proteins in blood plasma and the cerebrospinal fluid in human in vivo
The analysis of protein dynamics or turnover in patients has the potential to reveal altered protein recycling such as in Alzheimer disease, and to provide informative data regarding drug efficacy, or certain biological processes. The observed protein dynamics in a solid tissue or a fluid is the net...
ORGANISM(S): Homo Sapiens 
2025-04-30 | PXD047851 | panorama
ProteomicsStable Isotope Labeling by Amino acid in Vivo (SILAV)
Intravenous administration of stable isotope labeled amino acid ((13)C6-leucine) to humans recently made it possible to study the metabolism of specific biomarkers in cerebrospinal fluid (CSF) and in plasma using targeted mass spectrometry (MS). This labeling approach could be of great interest for ...
ORGANISM(S): Homo Sapiens 
2025-11-15 | PXD046142 | panorama
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