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ProteomicsCell Surface Engineering Enables Surfaceome Profiling
Understanding which proteins are presented at the cell surface is essential for ongoing therapeutic development, and to expand our basic understanding of biology. We envisioned the integration of cell surface engineering with radical-mediated protein biotinylation to profile cell surface proteins (C...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2022-05-06 | PXD031845 | Pride
Proximity labeling Surfaceome Pdac 
ProteomicsAPEX-Gal1 Labeled C2C12 Myoblasts
Myogenic differentiation is influenced by interactions at the cell surface involving the glycan binding protein galectin-1. Using a proximity labeling galectin-1 construct, we biotinylated and enriched galectin-1 interactors in mouse myoblasts, and analyzed them by LC/MS/MS to determine relevant gal...
ORGANISM(S): Mus musculus (Mouse) 
2021-07-05 | PXD026718 | Pride
Mouse Lc/msms Myoblasts 
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