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MetabolomicsLow chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk
Dysregulated extravillous trophoblast invasion and proliferation are known to increase the risk of recurrent spontaneous abortion (RSA); however, the underlying mechanism remains unclear. Herein, in our retrospective observational case-control study we show that villous samples from RSA patients, co...
2021-10-06 | MTBLS2148 | MetaboLights
GenomicsSplenic Marginal Zone Lymphoma with villous lymphocytes exome sequencing
Agilent whole exome hybridisation capture will be performed on genomic DNA derived from ~3 Splenic Marginal Zone Lymphoma with villous lymphocytes samples and matched normal DNA from the same patients. Samples will be multiplexed in one lane of Illumina HiSeq. Sequencing to a coverage of at least 30...
EGAS00001000139 | EGA
TranscriptomicsSharkey trophoblast
Transcriptional profiling comparison of human primary villous trophoblast and extra-villous trophoblast (VT and EVT respectively) cells, isolated from the placenta at 8 to 12 weeks gestation, with complimentary transcriptional profiling of choriocarcinoma cell lines JEG-3 and JAR. Based on phenotypi...
ORGANISM(S): Homo sapiens 
2011-04-28 | E-MTAB-429 | biostudies-arrayexpress
GenomicsPlacenta-specific genes and their regulation during villous trophoblast differentiation.
Placenta-specific genes and their regulation during villous trophoblast differentiation.
PRJNA535523 | ENA
GenomicsBDE-47 Transcriptomic Alterations in Human Primary Villous Cytrophoblasts
BDE-47 Transcriptomic Alterations in Human Primary Villous Cytrophoblasts
PRJNA414100 | ENA
ProteomicsH. sapiens First trimester placental villous explant 0conditioned media; galectin-7/BSA treatment; 2% O2
Identification of factors in conditioned media of first-trimester placental villous explants. Explants were cultured under hypoxia (2% O2), 5% CO2 in serum-free DMEM/F12 and treated with recombinant galectin-7 (1ug/ml) or vehicle control (BSA) for 72h. Identification of factors in conditioned media...
ORGANISM(S): Homo sapiens (Human) 
2021-04-20 | PXD019331 | Pride
Placenta Label free quantification Galectin-7/bsa treatment Villous 2% o2 Conditioned media 
TranscriptomicsTranscription profiling of human trophoblast cells isolated from first trimester human placentae and villous explant cultures
Invasion of cytotrophoblasts into uterine tissues is essential for placental development. To identify molecules regulating trophoblast invasion, mRNA signatures of purified villous (CTB, poor invasiveness) and extravillous (EVT, high invasiveness) trophoblasts isolated from first trimester human pla...
ORGANISM(S): Homo sapiens 
2009-01-30 | E-GEOD-9773 | biostudies-arrayexpress
ProteomicsUnraveling the matrix: Proteomic profiling reveals stromal ECM dysregulation in severe early-onset fetal growth restriction
Severe, early-onset fetal growth restriction with absent or reversed end-diastolic umbilical artery velocities (FGRa/r) is marked by profound placental vascular insufficiency, yet the role of the villous stromal extracellular matrix (ECM) in this pathology remains poorly defined. Here, we applied an...
ORGANISM(S): Homo sapiens (Human) 
2025-12-08 | PXD070632 | Pride
Proteomics Fetal growth restriction Pregnancy Fibrosis Collagen Extracellular matrix Placenta 
ProteomicsPrimary villous trophoblasts exposed to flame retardant BDE-47
We exposed primary villous trophoblasts to flame retardant BDE-47 (1, 5 uM) across three culture time points (15, 24, 39 hr).
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-07-23 | MSV000087870 | MassIVE
TranscriptomicsmicroRNA-array of human miscarriage chorionic villous tissue and controls
To identify the significant different gene, which maybe involved in the etiology of early miscarriage
ORGANISM(S): Homo sapiens 
2022-02-07 | E-MTAB-11443 | biostudies-arrayexpress
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