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TranscriptomicsThe G Protein-coupled Receptor P2Y14 Influences Insulin Release and Smooth Muscle Function in Mice
UDP-sugars were identified as extracellular signaling molecules, assigning a new function to these compounds in addition to their well defined role in intracellular substrate metabolism and storage. Previously regarded as an orphan receptor, the G protein-coupled receptor (GPCR) P2Y14 (GPR105) was f...
ORGANISM(S): Mus musculus 
2014-07-11 | E-GEOD-59285 | biostudies-arrayexpress
TranscriptomicsLeft ventricular myocardial transcriptomic profiling for target discovery in a rat model of pressure overload-induced heart failure
Left ventricular myocardial transcriptomic profiling was performed in rats subjected to transverse aortic constriction (TAC)-induced heart failure and sham-operated controls to investigate gene expression changes associated with pressure overload-induced cardiac remodeling. The dataset was used in s...
ORGANISM(S): Rattus norvegicus 
2026-06-11 | E-MTAB-17114 | biostudies-arrayexpress
GenomicsThe Habenular G-Protein-Coupled Receptor 151 regulates synaptic plasticity and nicotine intake
The Habenular G-Protein-Coupled Receptor 151 regulates synaptic plasticity and nicotine intake
PRJNA601907 | ENA
TranscriptomicsImpact of G protein versus beta-arrestin-dependent signal transduction at the FSH receptor (affy_fsh_human)
affy_fsh_human - affy_fsh_human - - G protein-coupled receptors (GPCR) are centrally involved in most physiological processes and are a major drug targets. They transduce extracellular signals inside the cells through at least two different mechanisms: i) the classical coupling to heterotrimeric G p...
ORGANISM(S): Homo sapiens 
2011-11-25 | E-GEOD-21982 | biostudies-arrayexpress
UnknownHuman cytomegalovirus-encoded G protein-coupled receptor (GPCR), UL78, regulates viral reactivation.
Not available
S-EPMC12157606 | biostudies-literature
UnknownHuman cytomegalovirus-encoded G protein-coupled receptor (GPCR) UL78 regulates viral reactivation.
Not available
S-EPMC12455920 | biostudies-literature
TranscriptomicsThe Habenular G-Protein-Coupled Receptor 151 regulates synaptic plasticity and nicotine intake
The habenula, an ancient small brain area in the epithalamus, densely expresses nicotinic acetylcholine receptors and is critical for nicotine intake and aversion. As such, identification of strategies to manipulate habenular activity may yield new approaches to treat nicotine addiction. Here we sho...
ORGANISM(S): Mus musculus 
2020-01-18 | GSE143854 | GEO
TranscriptomicsvGPCR and lytic KSHV time course in TIME cells
TIME cells either expressing KSHV-RTA or KSHV-vGPCR alone, or TIME cells infected with KSHV and lytically reactivated with RTA for 6, 12, or 20 hours. Keywords = KSHV Keywords = host shutoff Keywords = vGPCR
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-1406 | biostudies-arrayexpress
TranscriptomicsExpression data from HMC-1 mast cells
We demonstrate that the G protein Gi3 is the cellular target of the adenosine A3 receptor (A3R). By using a cell permeable peptide comprising the C-terminal end of Gαi3 fused to an importation sequence (ALL1) as a selective inhibitor of Gi3 signaling, we show that by coupling to Gi3, the A3R stimu...
ORGANISM(S): Homo sapiens 
2010-04-12 | E-GEOD-19888 | biostudies-arrayexpress
UnknownHuman and viral chemokines differentially modulate G protein signaling, β-arrestin recruitment and chemotaxis mediated by the viral G protein-coupled receptor ORF74.
Not available
S-EPMC12750907 | biostudies-literature
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