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MetabolomicsDifferential role of sphingomyelin in influenza virus, rhinovirus and SARS-CoV-2 infection of Calu-3 cells
Host cell lipids play a pivotal role in the pathogenesis of respiratory virus infection. However, a direct comparison of the lipidomic profile of influenza virus and rhinovirus infections is lacking. In this study, we first compared the lipid profile of influenza virus and rhinovirus infection in a ...
2022-11-15 | MTBLS2352 | MetaboLights
MetabolomicsTargeting the SREBP-dependent lipidomic reprogramming by virus infection for broad-spectrum therapeutic intervention
Viruses are obligate intracellular parasites that exploit the host metabolic machineries to meet their extraordinary biosynthetic demands. Integrative transcriptomic and lipidomic profiling confirmed that Middle East respiratory syndrome coronavirus (MERS-CoV) infection reprograms the host lipid met...
2018-11-26 | MTBLS762 | MetaboLights
ProteomicsInactivation of Influenza A virus under expiratory aerosol conditions is mediated by structural protein changes, as determined by whole virus mass-spectrometry.
Multiple respiratory viruses including Influenza A virus (IAV) can be transmitted via expiratory aerosol particles, and many studies have established that environmental conditions can affect viral infectivity during airborne transmission. Low aerosol pH was recently identified as a major factor infl...
ORGANISM(S): Influenza A virus (A/WSN/1933(H1N1)) 
2023-08-10 | PXD037176 | Pride
Influenza Heamaggluttinin Ph Hdx-ms Hatrix protein 1 
TranscriptomicsTranscriptome analysis of rice stripe virus-infected rice
Rice stripe virus (RSV) is one of the major virus diseases of rice in East Asia. Rice plants infected with RSV usually show symptoms such as chlorotic leaf stripes, weakness and senescence of leaves, and dwarfism. In order to characterize the host response to RSV infection at the gene expression lev...
ORGANISM(S): Oryza sativa Japonica Group 
2009-09-01 | E-GEOD-12681 | biostudies-arrayexpress
ProteomicsSpecimen Inactivation Methods for Proteomics – Comparisons of irradiation, chemical, and heat treatments on downstream serum analyses
Numerous studies have described the efficacy of heat inactivation, gamma irradiation, or treatment with guanidium-based chaotropic salts (e.g. TRIzol®) for pathogen inactivation of biological samples to ensure biosafety and biosecurity. However, the effect of these methods on the greater serum prote...
ORGANISM(S): Macaca mulatta (Rhesus macaque) 
2025-10-13 | PXD062367 | Pride
Dia Inactivation Gamma irradiation Rhesus Serum Trizol Primate 
Transcriptomics3-anhydro-6-hydroxy-ophiobolin A inhibits the replication of influenza A virus in vitro and in vivo
Influenza is a major cause of morbidity and mortality worldwide, and the emerging drug resistance poses an increasing challenge to the treatment of influenza virus infection. Therefore, the development of a novel antiviral drugs has become an urgent task to combat against the influenza viruses that ...
ORGANISM(S): Homo sapiens 
2015-11-05 | E-GEOD-58741 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of cultured human cells infected with African Swine Fever Virus (ASFV) to identify host genes required for replication of ASFV
African swine fever virus (ASFV) produces a fatal acute hemorrhagic fever in domesticated pigs that potentially is a worldwide economic threat. Using an expressed sequence tag (EST) library-based antisense method of random gene inactivation and a phenotypic screen for limitation of ASFV replication ...
ORGANISM(S): Homo sapiens 
2006-12-10 | E-SMDB-3898 | biostudies-arrayexpress
ProteomicsEfficient inactivation of virus in water by damaging viral protein and genome using pulsed corona discharge plasma
This study first evaluated the inactivation efficacy of PCDP using spring viremia of carp virus (SVCV) as models for viruses in water. As for the mechanism of virus inactivation, we used molecular tools and high-resolution mass spectrometry to determine reactions of viral proteins and genome after i...
ORGANISM(S): Carp Sprivivirus 
2021-02-06 | PXD024027 |
UnknownDetailed analysis of low temperature inactivation of respiratory syncytial virus.
Not available
S-EPMC11116427 | biostudies-literature
UnknownPlasmonic Enhancement of Selective Photonic Virus Inactivation.
Not available
S-EPMC5607298 | biostudies-literature
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